Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. - Wikidata - wikimedia - TriplyDB

Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.

Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.

http://www.wikidata.org/entity/Q33940612

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Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription.Ligand-independent activation of oestrogen receptor alpha by caveolin-1 The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth A conserved lysine in the estrogen receptor DNA binding domain regulates ligand activation profiles at AP-1 sites, possibly by controlling interactions with a modulating repressor Ligand-induced estrogen receptor alpha degradation by the proteasome: new actors?HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases BRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase Structural Basis for Ca2+-induced Activation and Dimerization of Estrogen Receptor by Calmodulin MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer Post-translational modification of nuclear co-repressor receptor-interacting protein 140 by acetylation Acquisition of sexual receptivity: roles of chromatin acetylation, estrogen receptor-alpha, and ovarian hormones.Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.Protein modifications as potential biomarkers in breast cancer.Recurrent t(2;2) and t(2;8) translocations in rhabdomyosarcoma without the canonical PAX-FOXO1 fuse PAX3 to members of the nuclear receptor transcriptional coactivator family.Minireview: The versatile roles of lysine deacetylases in steroid receptor signaling Liver X receptor ligands suppress ubiquitination and degradation of LXRalpha by displacing BARD1/BRCA1.The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention.Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer.Oestrogens and spermatogenesis.Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein.Palmitoylation: a protein S-acylation with implications for breast cancer.Research resource: comparison of gene profiles from wild-type ERα and ERα hinge region mutants.Estrogen receptor mutations and changes in downstream gene expression and signaling Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increased DNA binding.Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells SIRT1 is regulated by a PPAR{γ}-SIRT1 negative feedback loop associated with senescence.Estrogen receptors: orchestrators of pleiotropic cellular responses.Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors.Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?

P2860

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P2860

Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.

http://www.wikidata.org/entity/Q33940612

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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Direct acetylation of the estr ...... ation and hormone sensitivity.

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Direct acetylation of the estr ...... ation and hormone sensitivity.

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Direct acetylation of the estr ...... ation and hormone sensitivity.

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Direct acetylation of the estr ...... ation and hormone sensitivity.

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prefLabel

Direct acetylation of the estr ...... ation and hormone sensitivity.

@ast

Direct acetylation of the estr ...... ation and hormone sensitivity.

@en

P1433

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P1433

Journal of Biological Chemistry

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Direct acetylation of the estr ...... ation and hormone sensitivity.

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P2093

Albanese C

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Angeletti RH

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Fu M

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Fuqua SA

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Hopp T

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Kato S

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Katzenellenbogen BS

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Kushner PJ

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Lisanti MP

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Lopez GN

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P2860

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

Histone-like TAFs within the PCAF histone acetylase complex

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

Induction of cyclin D1 by simian virus 40 small tumor antigen

Structure and function of a human TAFII250 double bromodomain module

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

P304

18375-18383

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scholarly article

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10.1074/JBC.M100800200

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P407

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21

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P478

276

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2001-03-09T00:00:00Z

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11279135

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