The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain.
about
Imerslund-Gräsbeck syndrome (selective vitamin B(12) malabsorption with proteinuria)AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressorFrom bowel to kidneys: the role of cubilin in physiology and diseaseRequirement for Foxd3 in maintaining pluripotent cells of the early mouse embryoExpression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryoMolecular study of mouse peri-implantation development using the in vitro culture of aggregated inner cell massAmnion formation in the mouse embryo: the single amniochorionic fold model.Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complexInborn errors of cobalamin absorption and metabolism.Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endodermGenetically heterogeneous selective intestinal malabsorption of vitamin B12: founder effects, consanguinity, and high clinical awareness explain aggregations in Scandinavia and the Middle East.The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins.MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.Juvenile selective vitamin B₁₂ malabsorption: 50 years after its description-10 years of genetic testingLuminal expression of cubilin is impaired in Imerslund-Grasbeck syndrome with compound AMN mutations in intron 3 and exon 7.Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic patternBMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity.Novel compound heterozygous mutations in AMN cause Imerslund-Gräsbeck syndrome in two half-sisters: a case report.Regionally specific induction by the Spemann-Mangold organizer.Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo.Inherited cobalamin malabsorption. Mutations in three genes reveal functional and ethnic patterns.The developing chicken yolk sac acquires nutrient transport competence by an orchestrated differentiation process of its endodermal epithelial cellsLmbrd1 expression is essential for the initiation of gastrulationOct4 is required ~E7.5 for proliferation in the primitive streak.Molecular mechanisms of receptor-mediated endocytosis in the renal proximal tubular epithelium.Neural induction and early patterning in vertebrates.Agonists and Antagonists of TGF-β Family Ligands.The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells.Specific effect of 5-fluorouracil on alpha-fetoprotein gene expression during the in vitro mouse embryonic stem cell differentiation.Proximal tubule cell hypothesis for cardiorenal syndrome in diabetes.Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling.Lack of megalin expression in adult human terminal ileum suggests megalin-independent cubilin/amnionless activity during vitamin B12 absorptionActivation of epiblast gene expression by the hypoblast layer in the prestreak chick embryo.Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.Expression of amnionless in mouse testes and Leydig cells.
P2860
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P2860
The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The amnionless gene, essential ...... cellular cysteine-rich domain.
@ast
The amnionless gene, essential ...... cellular cysteine-rich domain.
@en
type
label
The amnionless gene, essential ...... cellular cysteine-rich domain.
@ast
The amnionless gene, essential ...... cellular cysteine-rich domain.
@en
prefLabel
The amnionless gene, essential ...... cellular cysteine-rich domain.
@ast
The amnionless gene, essential ...... cellular cysteine-rich domain.
@en
P2093
P356
P1433
P1476
The amnionless gene, essential ...... cellular cysteine-rich domain.
@en
P2093
Disteche CM
Kalantry S
Tomihara-Newberger C
P2888
P304
P356
10.1038/86912
P407
P577
2001-04-01T00:00:00Z
P6179
1042140124