DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair. - Wikidata - wikimedia - TriplyDB

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair.

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair.

http://www.wikidata.org/entity/Q33947027

about

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation Biochemical evidence for Ku-independent backup pathways of NHEJ Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction The mechanism of human nonhomologous DNA end joining Mutations in XRCC4 cause primary microcephaly, short stature and increased genomic instability Genetic evidence that the non-homologous end-joining repair pathway is involved in LINE retrotransposition The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.DNA ligase IV as a new molecular target for temozolomide Taking a Bad Turn: Compromised DNA Damage Response in Leukemia TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer The chicken as a model for large-scale analysis of vertebrate gene function.Genetic interactions between BLM and DNA ligase IV in human cells.Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells.Differential usage of alternative pathways of double-strand break repair in Drosophila.Developmental modulation of nonhomologous end joining in Caenorhabditis elegans.DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair.Dynamic mechanism of nick recognition by DNA ligase.Choosing the right path: does DNA-PK help make the decision?Nonhomologous chromosomal integration of foreign DNA is completely dependent on MUS-53 (human Lig4 homolog) in Neurospora.Analysis of the role of homology arms in gene-targeting vectors in human cells The role of the non-homologous end-joining pathway in lymphocyte development.Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks.Ovarian cancer and DNA repair: DNA ligase IV as a potential key.DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease.Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.Functional overlaps between XLF and the ATM-dependent DNA double strand break response.Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all.Influence of nuclear structure on the formation of radiation-induced lethal lesions.Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency.Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer.

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P2860

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair.

http://www.wikidata.org/entity/Q33947027

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

DNA ligase IV-deficient cells ...... NA double-strand break repair.

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DNA ligase IV-deficient cells ...... NA double-strand break repair.

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type

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DNA ligase IV-deficient cells ...... NA double-strand break repair.

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DNA ligase IV-deficient cells ...... NA double-strand break repair.

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DNA ligase IV-deficient cells ...... NA double-strand break repair.

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DNA ligase IV-deficient cells ...... NA double-strand break repair.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

DNA ligase IV-deficient cells ...... NA double-strand break repair.

@en

P2093

H Koyama

http://www.w3.org/2001/XMLSchema#string

N Adachi

http://www.w3.org/2001/XMLSchema#string

T Ishino

http://www.w3.org/2001/XMLSchema#string

Y Ishii

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P2860

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

Ku recruits the XRCC4-ligase IV complex to DNA ends

Yeast DNA ligase IV mediates non-homologous DNA end joining.

Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system

Deletion of Ku86 causes early onset of senescence in mice

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

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12109-12113

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scholarly article

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10.1073/PNAS.201271098

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P433

21

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98

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Shunichi Takeda

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2001-10-01T00:00:00Z

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11756991

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11593023

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59776

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