Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3.
about
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14Ovarian cancer, the coagulation pathway, and inflammationProstate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging rolesIGF-Binding Protein 2 - Oncogene or Tumor Suppressor?Insulin-like growth factor system in cancer: novel targeted therapiesSpecificity profiling of seven human tissue kallikreins reveals individual subsite preferencesThe emerging roles of human tissue kallikreins in cancerHuman tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression"Topological significance" analysis of gene expression and proteomic profiles from prostate cancer cells reveals key mechanisms of androgen responseInsulin-like growth factor binding proteins: a structural perspective.Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.Deciphering c-MYC-regulated genes in two distinct tissues.Development of recombinant inhibitors specific to human kallikrein 2 using phage-display selected substrates.Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology.Targeting of bone-derived insulin-like growth factor-II by a human neutralizing antibody suppresses the growth of prostate cancer cells in a human bone environment.Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer.Proteolytic degradation of insulin-like growth factor binding proteins by ovarian follicles: a control mechanism for selection of dominant follicles.Protease-activated drug development.The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers.The kallikrein world: an update on the human tissue kallikreins.The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition.Development of peptides specifically modulating the activity of KLK2 and KLK3.Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer.Perspectives in mammalian IGFBP-3 biology: local vs. systemic action.New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family.Metastasis of ovarian cancer is mediated by kallikrein related peptidases.Targeting kallikrein-related peptidases in prostate cancer.Selection of 2'F-modified RNA aptamers against prostate-specific antigen and their evaluation for diagnostic and therapeutic applications.Kallikrein-related peptidases targeted therapies in prostate cancer: perspectives and challenges.Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma.A functional variant in miR-143 promoter contributes to prostate cancer risk.Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation.PSA affects prostate cancer cell invasion in vitro and induces an osteoblastic phenotype in bone in vivo.Complex alternative splicing of the hKLK3 gene coding for the tumor marker PSA (prostate-specific-antigen).Identification of IGFBP-3 fragments generated by KLK2 and prevention of fragmentation by KLK2-inhibiting peptides.Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.Quantified KLK15 gene expression levels discriminate prostate cancer from benign tumors and constitute a novel independent predictor of disease progression.Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects.Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
P2860
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P2860
Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@ast
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@en
type
label
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@ast
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@en
prefLabel
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@ast
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@en
P2093
P2860
P1433
P1476
Insulin-like growth factor bin ...... human kallikreins hK2 and hK3.
@en
P2093
F Gauthier
R Tremblay
S Mazerbourg
P2860
P304
P356
10.1046/J.1432-1327.2001.02185.X
P407
P577
2001-05-01T00:00:00Z