Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400
about
Expression of Y53A-actin in Dictyostelium disrupts the cytoskeleton and inhibits intracellular and intercellular chemotactic signaling.Mutation of actin Tyr-53 alters the conformations of the DNase I-binding loop and the nucleotide-binding cleftPhosphorylation of actin Tyr-53 inhibits filament nucleation and elongation and destabilizes filaments.A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION.How actin initiates the motor activity of MyosinConformational flexibility of loops of myosin enhances the global bias in the actin-myosin interaction landscape.Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation
P2860
Q30496448-6E7E1813-204D-4BD2-A55E-22C989F5DA63Q33744656-0F0D05DD-B974-4B4D-8724-22A0B1573311Q35012504-0F61A7A8-3381-4B1B-BE07-0C7258A6DC30Q36444036-DB037F07-C519-4831-9069-1AAE7CD43BBAQ42412794-E87ADF6B-5829-4460-B4EF-F1D2B7FD814EQ53623102-D4FC898F-19E2-48BA-A9D3-FF9419C4FF73Q58087435-A5386C4C-1373-4943-B7FD-ADA3BBB0E040
P2860
Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Biological, biochemical, and k ...... yosin II: importance of ALA400
@ast
Biological, biochemical, and k ...... yosin II: importance of ALA400
@en
type
label
Biological, biochemical, and k ...... yosin II: importance of ALA400
@ast
Biological, biochemical, and k ...... yosin II: importance of ALA400
@en
prefLabel
Biological, biochemical, and k ...... yosin II: importance of ALA400
@ast
Biological, biochemical, and k ...... yosin II: importance of ALA400
@en
P2860
P356
P1476
Biological, biochemical, and k ...... yosin II: importance of ALA400
@en
P2093
P2860
P304
26974-26983
P356
10.1074/JBC.M504453200
P407
P577
2005-05-16T00:00:00Z