Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor.
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Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysisTasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumorsOverexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesisThrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrinAkt1 regulates pathological angiogenesis, vascular maturation and permeability in vivoAkt1 in endothelial cell and angiogenesisProcessing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumorsKeystone symposium: the role of microenvironment in tumor induction and progression, Banff, Canada, 5-10 February 2005Antiangiogenic mechanisms and factors in breast cancer treatmentExtracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.Mechanism of action and clinical activity of tasquinimod in castrate-resistant prostate cancerThrombospondins as key regulators of synaptogenesis in the central nervous systemTumor angiogenesis and vascular patterning: a mathematical modelCrystal structure of the TSP-1 type 1 repeatsExpression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression systemLow thrombospondin 2 expression is predictive of low tumor regression after neoadjuvant chemoradiotherapy in rectal cancer.ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismO-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulationCapillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signalingActivation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiationAngiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteinsImplanted microvessels progress through distinct neovascularization phenotypesIncreased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome.A new procedure for determining the genetic basis of a physiological process in a non-model species, illustrated by cold induced angiogenesis in the carpADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumorsCD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis.Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model.Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions.E2F-1 directly regulates thrombospondin 1 expression.Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressorsModulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B.Characterization of the MDSC proteome associated with metastatic murine mammary tumors using label-free mass spectrometry and shotgun proteomicsVariable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1.p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancersDown regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancerThrombospondin-1-derived 4N1K peptide expression is negatively associated with malignant aggressiveness and prognosis in urothelial carcinoma of the upper urinary tract.Regulation of thrombospondin1 by extracellular proteases.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.
P2860
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P2860
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@ast
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@en
type
label
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@ast
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@en
prefLabel
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@ast
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@en
P2093
P2860
P356
P1476
Thrombospondin-1 suppresses sp ...... lar endothelial growth factor.
@en
P2093
J C Rodriguez-Manzaneque
M A Ortega
M L Iruela-Arispe
P2860
P304
12485-12490
P356
10.1073/PNAS.171460498
P407
P577
2001-10-16T00:00:00Z