iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
about
Tylosis with oesophageal cancer: Diagnosis, management and molecular mechanismsEGF receptor ligands: recent advancesIn Vitro Model of the Epidermis: Connecting Protein Function to 3D StructurePhosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.iRhom2 mutation leads to aberrant hair follicle differentiation in mice.iRhoms; Its Functions and Essential Roles.Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.Discovery in genetic skin disease: the impact of high throughput genetic technologies150th Anniversary Series: Desmosomes and the Hallmarks of Cancer.Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosisDeletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phosholipase C γ1 and protein kinase C pathways.Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses.Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency.The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.Olmutinib-induced palmoplantar keratoderma.Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes.p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
P2860
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P2860
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@ast
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@en
type
label
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@ast
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@en
prefLabel
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@ast
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@en
P2093
P2860
P50
P356
P1476
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function
@en
P2093
Akemi Ishida-Yamamoto
Charlotte Simpson
Nihal Kaplan
Olivier Marches
Sarah L Etheridge
Spiro Getsios
P2860
P304
P356
10.1093/HMG/DDU120
P577
2014-03-18T00:00:00Z