Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
about
EZH2 in Bladder Cancer, a Promising Therapeutic TargetDeazaneplanocin a is a promising drug to kill multiple myeloma cells in their niche3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.Histone methylases as novel drug targets: developing inhibitors of EZH2.Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.Plasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma.Clonogenic multiple myeloma cells have shared stemness signature associated with patient survivalTargeting oncogenic and epigenetic survival pathways in lymphoma.Targeting of cancer stem cells by inhibitors of DNA and histone methylation.MMSET regulates expression of IRF4 in t(4;14) myeloma and its silencing potentiates the effect of bortezomib.Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myelomaHDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphomaEpstein-Barr virus-associated T/natural killer-cell lymphoproliferative disorder in children and young adults has similar molecular signature to extranodal nasal natural killer/T-cell lymphoma but shows distinctive stem cell-like phenotype.
P2860
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P2860
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@ast
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@en
type
label
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@ast
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@en
prefLabel
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@ast
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@en
P2093
P2860
P1433
P1476
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
@en
P2093
Chien-Shing Chen
Chonglei Bi
Gaofeng Huang
Jianbiao Zhou
Lip Lee Cheong
Shaw Cheng Liu
Wee Joo Chng
Zhigang Xie
P2860
P304
P356
10.1371/JOURNAL.PONE.0021583
P407
P577
2011-06-24T00:00:00Z