The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis, down-regulates the CXCR4 chemokine receptor and impairs migration of chronic lymphocytic leukemia cells
about
Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell-based microenvironment: pre-clinical evidence for its association with chronic lymphocytic leukemia treatments.Global histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patientsEffective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms.Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migrationTreatment options for high-risk chronic lymphocytic leukaemia.Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.Nuclear protein isoforms: implications for cancer diagnosis and therapy.The bone marrow microenvironment and leukemia: biology and therapeutic targeting.Potential of histone deacetylase inhibitors for bladder cancer treatment.Suppression of chronic lymphocytic leukemia progression by CXCR4 inhibitor WZ811.HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance.The role of G protein-coupled receptors in lymphoid malignancies.Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified.Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in hepatocellular carcinoma.
P2860
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P2860
The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis, down-regulates the CXCR4 chemokine receptor and impairs migration of chronic lymphocytic leukemia cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@ast
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@en
type
label
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@ast
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@en
prefLabel
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@ast
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@en
P2093
P2860
P1433
P1476
The histone deacetylase inhibi ...... nic lymphocytic leukemia cells
@en
P2093
Alain Delforge
Basile Stamatopoulos
Cécile De Bruyn
Dominique Bron
Laurence Lagneaux
Nathalie Meuleman
P2860
P304
P356
10.3324/HAEMATOL.2009.013847
P577
2010-02-09T00:00:00Z