about
Digitoxin and its analogs as novel cancer therapeuticsReal-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cellsRegulation of renal function and structure by the signaling Na/K-ATPasePulmonary epithelial barrier function: some new players and mechanismsExtracellular alkaline pH leads to increased metastatic potential of estrogen receptor silenced endocrine resistant breast cancer cellsLoss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65SCardiac glycoside activities link Na(+)/K(+) ATPase ion-transport to breast cancer cell migration via correlative SAR21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctionsNa,K-ATPase is the putative membrane receptor of hormone ouabainClaudins and the modulation of tight junction permeability.Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells.Use of cell-based screening to identify small-molecule compounds that modulate claudin-4 expression.Ouabain modulates ciliogenesis in epithelial cells.A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway.Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusionReactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium HandlingCheckpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression.The Na-K-ATPase α₁β₁ heterodimer as a cell adhesion molecule in epithelia.Membrane potential-dependent inhibition of the Na+,K+-ATPase by para-nitrobenzyltriethylammonium bromideSalt-inducible kinase 1 regulates E-cadherin expression and intercellular junction stability.Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability.The Na+-K+-ATPase as self-adhesion molecule and hormone receptor.The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells.Regulation of paracellular permeability: factors and mechanisms.Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function.Ouabain-induced alterations of the apical junctional complex involve α1 and β1 Na,K-ATPase downregulation and ERK1/2 activation independent of caveolae in colorectal cancer cells.Na⁺i,K⁺i-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts.On the Many Actions of Ouabain: Pro-Cystogenic Effects in Autosomal Dominant Polycystic Kidney Disease.Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells.Strain-dependent augmentation of tight-junction barrier function in human primary epidermal keratinocytes by Lactobacillus and Bifidobacterium lysates.Ouabain targets the unfolded protein response for selective killing of HepG2 cells during glucose deprivation.β1-Na(+),K(+)-ATPase gene therapy upregulates tight junctions to rescue lipopolysaccharide-induced acute lung injury.Zinc ions regulate opening of tight junction favouring efflux of macromolecules via the GSK3β/snail-mediated pathway.The C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology.Requirement of glycogenolysis for uptake of increased extracellular K+ in astrocytes: potential implications for K+ homeostasis and glycogen usage in brain.The effect of acute hypoxia on short-circuit current and epithelial resistivity in biopsies from human colon.Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells.The ubiquitous isoform of Na/K-ATPase (ATP1A1) regulates junctional proteins, connexin 43 and claudin 11 via Src-EGFR-ERK1/2-CREB pathway in rat Sertoli cells.EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ouabain modulates epithelial cell tight junction.
@ast
Ouabain modulates epithelial cell tight junction.
@en
type
label
Ouabain modulates epithelial cell tight junction.
@ast
Ouabain modulates epithelial cell tight junction.
@en
prefLabel
Ouabain modulates epithelial cell tight junction.
@ast
Ouabain modulates epithelial cell tight junction.
@en
P2093
P2860
P50
P356
P1476
Ouabain modulates epithelial cell tight junction
@en
P2093
Amparo Lazaro
Arturo Ponce
Catalina Flores-Maldonado
Isabel Larre
Liora Shoshani
Marcelino Cereijido
Ruth Rincon-Heredia
P2860
P304
11387-11392
P356
10.1073/PNAS.1000500107
P407
P50
P577
2010-06-04T00:00:00Z