Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleLoss of pRB causes centromere dysfunction and chromosomal instabilityRB1: a prototype tumor suppressor and an enigmaThe multiple connections between pRB and cell metabolismMolecular mechanisms underlying RB protein functionARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins.A context-specific role for retinoblastoma protein-dependent negative growth control in suppressing mammary tumorigenesis.Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblastsMechanisms of aneuploidy.A nontranscriptional role for Oct4 in the regulation of mitotic entryA Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.The genetics of osteosarcoma.Condensin II mutation causes T-cell lymphoma through tissue-specific genome instabilityRB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo.Mutation of the LXCXE binding cleft of pRb facilitates transformation by ras in vitro but does not promote tumorigenesis in vivoMad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.Inhibition of retinoblastoma mRNA degradation through Poly (A) involved in the neuroprotective effect of berberine against cerebral ischemiaTargeting Rb inactivation in cancers by synthetic lethality.Normal and disordered reticulocyte maturation.Structural and functional characterization of the acidic region from the RIZ tumor suppressor.Expression Analysis of Genes Involved in the RB/E2F Pathway in Astrocytic Tumors.Losing balance: the origin and impact of aneuploidy in cancerImplications of aneuploidy for stem cell biology and brain therapeuticsInactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancerLinking abnormal mitosis to the acquisition of DNA damageCyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.RB1, development, and cancer.Retinoblastoma: concerning its initiation and treatment.A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instabilityRB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1.Therapeutic relevance of the protein phosphatase 2A in cancer.Merotelic kinetochore attachment: causes and effects.pRB, a tumor suppressor with a stabilizing presence.Mechanisms of aneuploidy induction by RAS and RAF oncogenesConserved RB functions in development and tumor suppression.Chromosome instability and deregulated proliferation: an unavoidable duo.RB: mitotic implications of a tumour suppressor.Tumor suppressive pathways in the control of neurogenesis.Regulation of transcription and chromatin structure by pRB: here, there and everywhere.
P2860
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P2860
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@ast
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@en
type
label
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@ast
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@en
prefLabel
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@ast
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@en
P2093
P2860
P356
P1433
P1476
Mitotic chromosome condensatio ...... a protein is tumor-suppressive
@en
P2093
Alison L Martens
Courtney H Coschi
Frederick A Dick
Kieran Ritchie
Nathalie G Berube
Sarah M Francis
Subrata Chakrabarti
P2860
P304
P356
10.1101/GAD.1917610
P577
2010-06-15T00:00:00Z