The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln

The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln

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http://www.wikidata.org/entity/Q33954448
Rab27a: A key to melanosome transport in human melanocytesRab27a is an essential component of melanosome receptor for myosin VaMutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden miceEvidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5ACultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distributiondsu functions in a MYO5A-independent pathway to suppress the coat color of dilute miceThe murine dilute suppressor gene encodes a cell autonomous suppressor.Rab27a regulates the peripheral distribution of melanosomes in melanocytesDilute suppressor dsu acts semidominantly to suppress the coat color phenotype of a deletion mutation, dl20J, of the murine dilute locusA mutation in Rab27a causes the vesicle transport defects observed in ashen miceRabs and their effectors: achieving specificity in membrane trafficModifier genes and the plasticity of genetic networks in mice.Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes.The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulatorMelanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis.Melanoregulin (MREG) modulates lysosome function in pigment epithelial cellsThe Structure of Melanoregulin Reveals a Role for Cholesterol Recognition in the Protein's Ability to Promote Dynein Function
P2860

The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln

Item
http://www.wikidata.org/entity/Q33954448
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@ast
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@en
type
label
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@ast
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@en
prefLabel
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@ast
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@en
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932
P1433
P1476
The murine dilute suppressor g ...... cyte morphology, d, ash and ln
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932