Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest - Wikidata - wikimedia - TriplyDB

Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

http://www.wikidata.org/entity/Q33958962

about

Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma Bmi1, stem cells, and senescence regulation Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.Mammary epithelial cell transformation: insights from cell culture and mouse models.Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation.Immortalization of Primary Keratinocytes and Its Application to Skin Research Broad epigenetic signature of maternal care in the brain of adult rats Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a.Quantitative assessment of promoter hypermethylation during breast cancer development Sequence-specific DNA binding activity of RNA helicase A to the p16INK4a promoter.DNA methylation, methyltransferases, and cancer.A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray Epigenomic consequences of immortalized plant cell suspension culture.Asymmetric strand segregation: epigenetic costs of genetic fidelity?Homeostatic maintenance of allele-specific p16 methylation in cancer cells accompanied by dynamic focal methylation and hydroxymethylation.Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancer.Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies.H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells A 115-bp MethyLight assay for detection of p16 (CDKN2A) methylation as a diagnostic biomarker in human tissues.Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis.EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.Gene silencing in mammalian cells and the spread of DNA methylation.Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells.Mapping of the methylation pattern of the hMSH2 promoter in colon cancer, using bisulfite genomic sequencing.What has senescence got to do with cancer?Gene-promoter hypermethylation as a biomarker in lung cancer.Methylation of TIMP3 in esophageal squamous cell carcinoma Familial and racial determinants of tumour suppressor genes promoter hypermethylation in breast tissues from healthy women.Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells.Doxycycline-Regulated p16MTS1 Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16.Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density.Silencing of mouse Aprt is a gradual process in differentiated cells.Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA.Cloning of the 5' upstream region of the rat p16 gene and its role in silencing.Characterization of immortalized human mammary epithelial cell line HMEC 2.6.

P2860

Q21142611-8CDAD624-6765-4F04-8EF5-5DEFB8CFA1D3 Q21563424-1003F512-C85F-4BBD-BF4A-5C96FA602DE1 Q24614474-445FFFA2-4301-4CD0-914A-F21ABC6F3A8E Q24794569-4960208F-C4D9-4C8E-A920-9F997EDACE64 Q24810846-80ECC15B-0E96-4611-BE90-233D417FC7C4 Q25256949-55B93B1C-7AD7-41DB-9C3A-D07415C9F3BC Q26786026-91AA6B73-2921-471F-AE3C-ECB3D59E0A17 Q27314001-F6A199A7-AFA8-42FB-9475-9AC3A9BD5201 Q28215348-B0969508-0958-4AB0-B049-CF1A7CCFB1DC Q28361844-F4E6B4BF-A013-4FE5-973A-7EE7E9D756C3 Q30476274-1D184877-4CB9-46EB-9BF9-CF4FBCD000E8 Q30811494-A2BCF627-850D-43AB-BFCA-93080D4B6C8E Q30945379-9F3E7037-F847-456C-82D0-042DF1792C9F Q30993657-0C0EA4B1-59C0-4BCF-9207-77AEF1CE0F64 Q33317627-87063D1F-5206-489D-9977-4B80160BBE97 Q33391940-897B03F4-6C85-4E26-9D61-88BB4E33224C Q33463276-8DAF72AE-B06C-49F3-A8A9-1822964BF15A Q33610681-38E569AF-4B2C-420A-B708-746A61B12579 Q33820209-8213F1AD-9C99-4C36-BC1B-B09FFCC7877B Q33892935-181DE0B5-B982-4D26-82B3-1D60BA5C24C0 Q33897945-999345E2-42FC-427D-90C7-89AB7EF865CF Q33899068-FF9BABC9-86D2-4121-B7FA-DDE3D3114BFB Q33914526-D1AFA520-FDDD-4737-9EF1-D01BD44515EE Q34256946-6BE39654-95E3-4732-A7B1-55D93070A858 Q34288822-528C80B2-C5F5-4AE4-B090-004BA9382210 Q34770520-069EBEAA-2302-46F0-A7DC-C19ABC13678B Q34883526-2794BF07-8A0F-4658-B0F0-3F6653649B4F Q35039395-73C7BE59-1BA6-4391-8D8E-4CA3B8F594AF Q35585808-17118E88-DC39-4DDB-B481-E82B13F12A53 Q35877182-EE3CC8E5-AEFE-4204-B0FF-FAF11F1B737A Q37174136-5C3F7A56-867F-46F0-9C8C-45EDCC769A29 Q37310981-A4EEDD65-9E35-45F3-86F1-9BD81D768C5F Q37473906-C65FB52F-CC01-42C8-8931-FEC209E60AA1 Q37667766-75F20E17-7057-45E5-93F2-D48F372AF7B1 Q39753460-D789DEEF-A9D5-4DF4-ADD2-5A9EE3E3F013 Q39787851-076EDE25-F082-4F14-9F2C-CAEE616AF364 Q39845790-46FC7C2A-5960-49D8-B29C-1CF8523FFAB6 Q40310619-06F54A9E-056D-4A8C-9DBB-3E306B8F2B6F Q40692246-F4D4976A-D865-4FBD-BA8A-5A64376F1EC6 Q42516678-BB75FD22-8D7C-4DEF-8081-29D791156D52

P2860

Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

http://www.wikidata.org/entity/Q33958962

description

1999 nî lūn-bûn

@nan

1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Progressive region-specific de ...... escape from M(0) growth arrest

@ast

Progressive region-specific de ...... escape from M(0) growth arrest

@en

type

label

Progressive region-specific de ...... escape from M(0) growth arrest

@ast

Progressive region-specific de ...... escape from M(0) growth arrest

@en

prefLabel

Progressive region-specific de ...... escape from M(0) growth arrest

@ast

Progressive region-specific de ...... escape from M(0) growth arrest

@en

P1433

Q33958962-0893EBE9-6244-4C39-A4CB-7C1D982ACE6F

P1476

Q33958962-3CDBA336-7530-41B6-9D13-C7066E063D05

P2093

Q33958962-2AD2D4A4-8495-4DAD-B0A8-D5389947F439

Q33958962-3CF314C3-24F7-462C-9EAC-7B1A6AB54191

Q33958962-3F2BB6C7-8F2F-407A-B8C7-5C60063594C0

Q33958962-CE5ACA29-965A-4DF1-BF43-D0B42EA71BAB

P2860

Q33958962-0709CA97-653E-4700-8E89-3C1DFE37E92D

Q33958962-09173957-382A-4EA5-8AAA-4B9ECDF6DB86

Q33958962-0E03E077-9FB5-4022-8B52-6DD6F530E659

Q33958962-0E679C49-7A05-418E-BEB5-6A41E5118B64

Q33958962-16E15A97-A6AA-46AC-A5FC-713F2FBDC14D

Q33958962-19F68C40-1BBF-4F15-B769-5751CBF2736E

Q33958962-1AC1D800-EDE5-4DE9-AE55-A858A85DFC06

Q33958962-2D4FE734-DE8F-489C-AC3E-F2B973189CDA

Q33958962-3664C02F-415C-4F28-9E85-B25D2C48B34D

Q33958962-398556FC-B6F4-470D-8B56-D491DCDF300D

P304

Q33958962-9D5AF8F9-AD4C-44A8-BEE7-8FF73F025B70

P31

Q33958962-EBC37E8C-888F-459E-91A0-F94FC01344BD

P356

Q33958962-A58A9E36-9102-4913-95C0-AD098B351B33

P407

Q33958962-63F156F2-0898-4739-9A8A-436A772EAE5B

P433

Q33958962-BD7BAF18-4220-43FE-9A5C-BE0A9F025DF6

P478

Q33958962-100B4DB6-ECCE-473C-BE5B-13C9F0A53230

P577

Q33958962-AB868509-3357-484A-A05B-1860A3B36654

P698

Q33958962-30D181D3-C176-4478-866B-52AFB205A035

P932

Q33958962-F04B273E-B540-44F7-9E6A-685B54714A4F

P356

P1433

Molecular and Cellular Biology

P1476

Progressive region-specific de ...... escape from M(0) growth arrest

@en

P2093

B J Reid

http://www.w3.org/2001/XMLSchema#string

D A Galloway

http://www.w3.org/2001/XMLSchema#string

D J Wong

http://www.w3.org/2001/XMLSchema#string

S A Foster

http://www.w3.org/2001/XMLSchema#string

P2860

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

Cancer cell cycles

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types.

Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns.

Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability.

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

P304

5642-5651

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.19.8.5642

http://www.w3.org/2001/XMLSchema#string

P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P577

1999-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10409753

http://www.w3.org/2001/XMLSchema#string

P932

84416

http://www.w3.org/2001/XMLSchema#string