NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase.
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Hostile takeovers: viral appropriation of the NF-kB pathwayIntracellular events and cell fate in filovirus infectionActivation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific mannerTRAF family proteins link PKR with NF-kappa B activationProtein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.Modular structure of PACT: distinct domains for binding and activating PKRPathogen recognition and inflammatory signaling in innate immune defensesRAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infectionImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionDoes protein kinase R mediate TNF-alpha- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism?Alphaherpesvirus Subversion of Stress-Induced Translational ArrestTransfection of single-stranded hepatitis A virus RNA activates MHC class I pathwayWest Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKRSpecific deficiency in nuclear factor-kappaB activation in neurons of the central nervous systemPhosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosisMechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosisThe protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxinDouble-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infectionQuantitative Proteomic Analysis of BHK-21 Cells Infected with Foot-and-Mouth Disease Virus Serotype Asia 1Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signalingThe small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alphaP58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenaseAndes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis.Activation of NF-kB pathway by virus infection requires Rb expression.The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling.Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysisEffects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines.PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulatorRole of p58IPK in Endoplasmic Reticulum Stress-associated Apoptosis and InflammationOrgan-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.Malignant transformation of B lymphoma cell line BJAB by Epstein-Barr virus-encoded small RNAs.Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programsIRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNABuilding better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunityThe protein kinase PKR: a molecular clock that sequentially activates survival and death programs.Molecular pathways in virus-induced cytokine production.Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicinPACT and PKR: turning on NF-kappa B in the absence of virus.
P2860
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P2860
NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
@wuu
name
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@ast
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@en
type
label
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@ast
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@en
prefLabel
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@ast
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@en
P2093
P2860
P1476
NF-kappaB activation by double ...... ing kinase and IkappaB kinase.
@en
P2093
B R Williams
J A DiDonato
M Zamanian-Daryoush
T H Mogensen
P2860
P304
P356
10.1128/MCB.20.4.1278-1290.2000
P407
P577
2000-02-01T00:00:00Z