Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells
about
3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signalingIncreased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsiesInduction of homologue of Slimb ubiquitin ligase receptor by mitogen signalingX-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1)BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.Identification of NF-kappaB-dependent gene networks in respiratory syncytial virus-infected cells.Nitroglycerin alters matrix remodeling proteins in THP-1 human macrophages and plasma metalloproteinase activity in rats.An old kinase on a new path: Raf and apoptosis.Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors.Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug.Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cellsATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism.Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysisIkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation.Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.NF-κB in cancer therapy.PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine networkNuclear factor-κB signaling pathway is involved in phospholipase Cε-regulated proliferation in human renal cell carcinoma cells.Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytesHyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death.Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesisFormyl peptide-receptor like-1 requires lipid raft and extracellular signal-regulated protein kinase to activate inhibitor-kappa B kinase in human U87 astrocytoma cells.Autocrine secretion of osteopontin results in degradation of I kappa B in Bcr-Abl-expressing cells.Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages.Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IkappaBbeta.Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation.IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma.Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathways.Constitutive activation of NF-kappaB in Ki-ras-transformed prostate epithelial cells.KRAS mutation and NF-κB activation indicates tolerance of chemotherapy and poor prognosis in colorectal cancer.DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-κB pathway in colorectal cancer.Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1.
P2860
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P2860
Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@ast
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@en
type
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Role of the IkappaB kinase com ...... of rat liver epithelial cells
@ast
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@en
prefLabel
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@ast
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@en
P2093
P2860
P1476
Role of the IkappaB kinase com ...... of rat liver epithelial cells
@en
P2093
A L Oliver
F Mercurio
G E Sonenshein
S S Thorgeirsson
P2860
P304
P356
10.1128/MCB.20.15.5381-5391.2000
P407
P577
2000-08-01T00:00:00Z