Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity.
about
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.Differential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesisMurine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?Genetic and epigenetic changes in sporadic endocrine tumors: parathyroid tumorsAn important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferationTumor suppressors and cell-cycle proteins in lung cancerDifferential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesisMenin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4cDifferential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expressionGenetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell numberMutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cellsA mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumorsMenin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitusp21 in cancer: intricate networks and multiple activitiesAn essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stressComparative analysis of microarray data identifies common responses to caloric restriction among mouse tissuesCharacterisation of prostate cancer lesions in heterozygous Men1 mutant miceConditional deletion of p53 and Rb in the renin-expressing compartment of the pancreas leads to a highly penetrant metastatic pancreatic neuroendocrine carcinoma.Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferationControl of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d)Genetically engineered mouse models of pituitary tumorsGenetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in miceMEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.P53 mutations in thyroid carcinoma: tidings from an old foe.p27 Loss Is Associated with Poor Prognosis in Gastroenteropancreatic Neuroendocrine Tumors.ARF mutation accelerates pituitary tumor development in Rb+/- mice.An opposite effect of the CDK inhibitor, p18(INK4c) on embryonic stem cells compared with tumor and adult stem cells.RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent mannerHyperparathyroid genes: sequences reveal answers and questions.Cross signaling, cell specificity, and physiology.p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control.Glucose-dependent insulinotropic peptide receptor overexpression in adrenocortical hyperplasia in MEN1 syndrome without loss of heterozygosity at the 11q13 locus.Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.P21Waf1 control of epithelial cell cycle and cell fate.Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studiesType 2 diabetes and the aging pancreatic beta cell.p21 delays tumor onset by preservation of chromosomal stability.
P2860
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P2860
Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity.
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Functional collaboration betwe ...... h distinct tissue specificity.
@ast
Functional collaboration betwe ...... h distinct tissue specificity.
@en
type
label
Functional collaboration betwe ...... h distinct tissue specificity.
@ast
Functional collaboration betwe ...... h distinct tissue specificity.
@en
prefLabel
Functional collaboration betwe ...... h distinct tissue specificity.
@ast
Functional collaboration betwe ...... h distinct tissue specificity.
@en
P2093
P2860
P1476
Functional collaboration betwe ...... h distinct tissue specificity.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.16.6147-6158.2000
P407
P577
2000-08-01T00:00:00Z