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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

http://www.wikidata.org/entity/Q33973651

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Diversity of intervertebral disc cells: phenotype and function TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue A phased rehabilitation protocol for athletes with lumbar intervertebral disc herniation Notochordal cell-derived therapeutic strategies for discogenic back pain.Col2CreER(T2), a mouse model for a chondrocyte-specific and inducible gene deletion.Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia.Needle puncture in rabbit functional spinal units alters rotational biomechanics.Loss of notochordal cell phenotype in 3D-cell cultures: implications for disc physiology and disc repair.Intact glycosaminoglycans from intervertebral disc-derived notochordal cell-conditioned media inhibit neurite growth while maintaining neuronal cell viability.Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration The evolutionary importance of cell ratio between notochordal and nucleus pulposus cells: an experimental 3-D co-culture study.Dynamic Compression Effects on Immature Nucleus Pulposus: a Study Using a Novel Intelligent and Mechanically Active Bioreactor.Cervical disc deformation during flexion-extension in asymptomatic controls and single-level arthrodesis patients.Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development.Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model.Degeneration and regeneration of the intervertebral disc: lessons from development.Reconstruction of an in vitro niche for the transition from intervertebral disc development to nucleus pulposus regeneration.Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration.Repeated exposure to high-frequency low-amplitude vibration induces degeneration of murine intervertebral discs and knee joints.Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs.Formation, function, and exhaustion of notochordal cytoplasmic vacuoles within intervertebral disc: current understanding and speculation.Using notochordal cells of developmental origin to stimulate nucleus pulposus cells and bone marrow stromal cells for intervertebral disc regeneration.Role of p38-MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture.Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of the Intervertebral Disc.Functional impact of integrin α5β1 on the homeostasis of intervertebral discs: a study of mechanotransduction pathways using a novel dynamic loading organ culture system.Hyperosmolarity induces notochordal cell differentiation with aquaporin3 upregulation and reduced N-cadherin expression.A Substance Exchanger-Based Bioreactor Culture of Pig Discs for Studying the Immature Nucleus Pulposus.Intermittent Cyclic Mechanical Tension Promotes Degeneration of Endplate Cartilage via the Nuclear Factor-κB Signaling Pathway: an in Vivo Study.Effects of shear force on intervertebral disc: an in vivo rabbit study.A rat tail temporary static compression model reproduces different stages of intervertebral disc degeneration with decreased notochordal cell phenotype.

P2860

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P2860

Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

http://www.wikidata.org/entity/Q33973651

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

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European Spine Journal

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Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study

@en

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Georg W Omlor

http://www.w3.org/2001/XMLSchema#string

Markus Kroeber

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Thorsten Guehring

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P2860

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

Matrix gene expression analysis and cellular phenotyping in chordoma reveals focal differentiation pattern of neoplastic cells mimicking nucleus pulposus development.

New in vivo measurements of pressures in the intervertebral disc in daily life.

Compression-induced changes in intervertebral disc properties in a rat tail model.

Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy.

Expression of type II procollagens during development of the human intervertebral disc.

The role of disc cell heterogeneity in determining disc biochemistry: a speculation.

Towards a better understanding of low-back pain: a review of the mechanics of the lumbar disc.

The notochordal cell in the nucleus pulposus: a review in the context of tissue engineering.

Nutrition of the intervertebral disc.

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10.1007/S00586-009-1217-0

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Wiltrud Richter

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