Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
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Biological phosphoryl-transfer reactions: understanding mechanism and catalysisNMR structure of the A730 loop of the Neurospora VS ribozyme: insights into the formation of the active siteA Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme CatalysisNMR Localization of Divalent Cations at the Active Site of the Neurospora VS Ribozyme Provides Insights into RNA–Metal-Ion InteractionsCrystal structure and mechanistic investigation of the twister ribozymeChemistry and Biology of Self-Cleaving RibozymesThe glmS ribozyme cofactor is a general acid-base catalystUse of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small moleculesDo the hairpin and VS ribozymes share a common catalytic mechanism based on general acid-base catalysis? A critical assessment of available experimental data.Crystal structure of the Varkud satellite ribozyme.A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.Molecular recognition of 6'-N-5-hexynoate kanamycin A and RNA 1x1 internal loops containing CA mismatches.Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulationsBase ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world.Heavy atom labeled nucleotides for measurement of kinetic isotope effectsRole of pK(a) of nucleobases in the origins of chemical evolutionMultiscale methods for computational RNA enzymology.Catalysis by the nucleolytic ribozymes.Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage.Nucleic acid catalysis: metals, nucleobases, and other cofactors.Insights into RNA structure and dynamics from recent NMR and X-ray studies of the Neurospora Varkud satellite ribozyme.Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes.The structure of a nucleolytic ribozyme that employs a catalytic metal ion.Charged nucleobases and their potential for RNA catalysis.Rational engineering of the Neurospora VS ribozyme to allow substrate recognition via different kissing-loop interactions.Crystal structure of Pistol, a class of self-cleaving ribozyme.General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.A remarkably stable kissing-loop interaction defines substrate recognition by the Neurospora Varkud Satellite ribozyme.Substrate and enzyme functional groups contribute to translational quality control by bacterial prolyl-tRNA synthetase.Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis.The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure.Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture.Additional roles of a peripheral loop-loop interaction in the Neurospora VS ribozyme.Mechanisms of RNA catalysis.A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer.The synthesis, conformation and hydrolytic stability of an N,S-bridging thiophosphoramidate analogue of thymidylyl-3′,5′-thymidine
P2860
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P2860
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@ast
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@en
type
label
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@ast
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@en
prefLabel
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@ast
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@en
P2093
P2860
P356
P1476
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
@en
P2093
David M J Lilley
John K Frederiksen
Joseph A Piccirilli
Nan-Sheng Li
Timothy J Wilson
P2860
P304
11751-11756
P356
10.1073/PNAS.1004255107
P407
P577
2010-06-14T00:00:00Z