PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. - Wikidata - wikimedia - TriplyDB

PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.

PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.

http://www.wikidata.org/entity/Q33981871

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Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration.Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression IL-27 inhibits pathophysiological intraocular neovascularization due to laser burn.VEGF-independent angiogenic pathways induced by PDGF-C.Targeting of junctional adhesion molecule-C inhibits experimental choroidal neovascularization Morpholino-mediated increase in soluble Flt-1 expression results in decreased ocular and tumor neovascularization Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration.VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.Inhibition of protein kinase C enhances angiogenesis induced by platelet-derived growth factor C in hyperglycemic endothelial cells.Development of gene therapy for treatment of age-related macular degeneration.PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway.PDGFR-β as a positive regulator of tissue repair in a mouse model of focal cerebral ischemia Subretinal AAV2.COMP-Ang1 suppresses choroidal neovascularization and vascular endothelial growth factor in a murine model of age-related macular degeneration.PDGFRα plays a crucial role in connective tissue remodeling.Hepatic stellate cells in liver development, regeneration, and cancer.Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat Detection of aqueous VEGF concentrations before and after intravitreal injection of anti-VEGF antibody using low-volume sampling paper-based ELISA.PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently.The abluminal endothelial membrane in neurovascular remodeling in health and disease.Platelet-derived growth factors and their receptors: structural and functional perspectives.Pathogenetic significance and possibility as a therapeutic target of platelet derived growth factor.Microenvironmental regulation of tumour angiogenesis.Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts.A hypoxia-responsive glial cell-specific gene therapy vector for targeting retinal neovascularization.The fibrotic microenvironment as a heterogeneity facet of hepatocellular carcinoma.Angiogenesis and expression of PDGF-C, VEGF, CD105 and HIF-1α in human glioblastoma.PDGF/PDGFR axis in the neural systems.Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation.

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PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.

http://www.wikidata.org/entity/Q33981871

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

PDGF-CC blockade inhibits path ...... ellular and molecular targets.

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PDGF-CC blockade inhibits path ...... ellular and molecular targets.

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type

label

PDGF-CC blockade inhibits path ...... ellular and molecular targets.

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PDGF-CC blockade inhibits path ...... ellular and molecular targets.

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PDGF-CC blockade inhibits path ...... ellular and molecular targets.

@ast

PDGF-CC blockade inhibits path ...... ellular and molecular targets.

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PNAS.1004143107

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Proceedings of the National Academy of Sciences of the United States of America

P1476

PDGF-CC blockade inhibits path ...... cellular and molecular targets

@en

P2093

Anil Kumar

http://www.w3.org/2001/XMLSchema#string

Baoying Liu

http://www.w3.org/2001/XMLSchema#string

Bin Wang

http://www.w3.org/2001/XMLSchema#string

Chunsik Lee

http://www.w3.org/2001/XMLSchema#string

Fan Zhang

http://www.w3.org/2001/XMLSchema#string

Johan Lennartsson

http://www.w3.org/2001/XMLSchema#string

Lijin Dong

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Pachiappan Arjunan

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Peter Colosi

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Piotr Wardega

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P2860

PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways

A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling

Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma

Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts.

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12216-12221

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scholarly article

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10.1073/PNAS.1004143107

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27

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107

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J. Silvio Gutkind

Robert N. Fariss

Arvydas Maminishkis

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2010-06-21T00:00:00Z

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44691346

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20566880

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