Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.
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Animal Models for HIV Cure ResearchConsiderations in the development of nonhuman primate models of combination antiretroviral therapy for studies of AIDS virus suppression, residual virus, and curative strategiesKinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infectionsAntibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed MacaquesInhibitory potential of subpopulations of CD8+ T cells in HIV-1-infected elite suppressorsImmune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts.Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1Nonhuman primate models for HIV cure research.Using the pathogenic and nonpathogenic nonhuman primate model for studying non-AIDS comorbidities.Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses.Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research.Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo.Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection.Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal TissuesElite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs.Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routesHIV-1 transcription and latency: an update.Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaquesInvestigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS.Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaquesHLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice.Dynamics of innate immunity are key to chronic immune activation in AIDS.Eliminating the HIV reservoir.The implications of viral reservoirs on the elite control of HIV-1 infection.Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy.Kill: boosting HIV-specific immune responses.Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells.Role of Different Subpopulations of CD8+ T Cells during HIV Exposure and Infection.Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice.Cutting Edge: T Regulatory Cell Depletion Reactivates Latent Simian Immunodeficiency Virus (SIV) in Controller Macaques While Boosting SIV-Specific T Lymphocytes.Primary CD8+ T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+ T cells.The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8⁺ T cell responses.Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.The Antiviral Immune Response and Its Impact on the HIV-1 Reservoir.The dynamics of SIV 2-LTR Circles in the Presence and Absence of CD8+ Cells.Regulatory T Cells As Potential Targets for HIV Cure Research.Epigenetic Modulation of CD8⁺ T Cell Function in Lentivirus Infections: A Review.
P2860
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P2860
Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@ast
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@en
type
label
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@ast
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@en
prefLabel
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@ast
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@en
P2093
P2860
P50
P1433
P1476
Functional cure of SIVagm infe ...... verted by CD8+ cell depletion.
@en
P2093
Daniel Mandell
Jan Kristoff
Rajeev Gautam
Ronald S Veazey
Thaidra Gaufin
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002170
P577
2011-08-04T00:00:00Z