p53 proteasomal degradation: poly-ubiquitination is not the whole story.
about
NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b)Phosphorylation regulates the ubiquitin-independent degradation of yeast Pah1 phosphatidate phosphatase by the 20S proteasome.Quinone reductase acts as a redox switch of the 20S yeast proteasome.Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination.Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosisUnderstanding the mechanism of proteasome 20S core particle gating.20S proteasomes and protein degradation "by default".Split T cell tolerance against a self/tumor antigen: spontaneous CD4+ but not CD8+ T cell responses against p53 in cancer patients and healthy donors.Chloroquine binding reveals flavin redox switch function of quinone reductase 2.The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells.A small ribosomal subunit (SSU) processome component, the human U3 protein 14A (hUTP14A) binds p53 and promotes p53 degradation.White spot syndrome virus open reading frame 222 encodes a viral E3 ligase and mediates degradation of a host tumor suppressor via ubiquitination.Ubiquitin and ubiquitin-like modifications of the p53 family.Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer.MG132 inhibition of proteasome blocks apoptosis induced by severe DNA damage.Coping with stress: multiple ways to activate p53.Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.Versatile functions of p53 protein in multicellular organismsThe tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapyHypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.p53 polymorphisms: cancer implications.Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.New roles of flavoproteins in molecular cell biology: an unexpected role for quinone reductases as regulators of proteasomal degradation.Harmonic oscillations in homeostatic controllers: Dynamics of the p53 regulatory system.Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1Avenanthramides inhibit proliferation of human colon cancer cell lines in vitro.Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.Effects of stability on the biological function of p53.Ubiquitin-independent proteasomal degradation of Fra-1 is antagonized by Erk1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer.Degradation of HNE-modified proteins--possible role of ubiquitin.c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.Comparative proteomic analysis of cat eye syndrome critical region protein 1- function in tumor-associated macrophages and immune response regulation of glial tumors
P2860
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P2860
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@ast
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@en
type
label
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@ast
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@en
prefLabel
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@ast
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@en
P356
P1433
P1476
p53 proteasomal degradation: poly-ubiquitination is not the whole story.
@en
P2093
Yosef Shaul
P304
P356
10.4161/CC.4.8.1900
P577
2005-08-07T00:00:00Z