The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target.
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Isolation and characterization of type I signal peptidase of different malaria parasites.Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanismStructure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaSStructure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus PolymerisationThe lspA gene, encoding the type II signal peptidase of Rickettsia typhi: transcriptional and functional analysisPseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulenceThe Borrelia afzelii outer membrane protein BAPKO_0422 binds human factor-H and is predicted to form a membrane-spanning β-barrelBdellovibrio bacteriovorus strains produce a novel major outer membrane protein during predacious growth in the periplasm of prey bacteriaDiscovery of substrate for type I signal peptidase SpsB from Staphylococcus aureus.Data-mining approaches reveal hidden families of proteases in the genome of malaria parasiteProtein complexes of the Escherichia coli cell envelope.Identification of protein secretion systems and novel secreted proteins in Rhizobium leguminosarum bv. viciae.Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal peptide cleavageFlanking signal and mature peptide residues influence signal peptide cleavage.How Listeria monocytogenes organizes its surface for virulenceNovel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxinH35L in Escherichia coliA major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis.Topology, dimerization, and stability of the single-span membrane protein CadCThe DotA protein from Legionella pneumophila is secreted by a novel process that requires the Dot/Icm transporterThe sortase A substrates FnbpA, FnbpB, ClfA and ClfB antagonize colony spreading of Staphylococcus aureus.Broad-spectrum antibiotic activity of the arylomycin natural products is masked by natural target mutationsInitial efforts toward the optimization of arylomycins for antibiotic activity.Molecular and functional analysis of the lepB gene, encoding a type I signal peptidase from Rickettsia rickettsii and Rickettsia typhi.Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidaseExpressed protein ligation using an N-terminal cysteine containing fragment generated in vivo from a pelB fusion protein.Some lessons from Rickettsia genomics.Interactions between folding factors and bacterial outer membrane proteins.Mechanism of action of the arylomycin antibiotics and effects of signal peptidase I inhibitionProteomic insights into intra- and intercellular plant-bacteria symbiotic association during root nodule formationEfforts toward broadening the spectrum of arylomycin antibiotic activity.Protein export systems of Mycobacterium tuberculosis: novel targets for drug development?Signal peptidase I: cleaving the way to mature proteins.Bacterial type I signal peptidases as antibiotic targets.Microbial and fungal protease inhibitors--current and potential applications.Proteases in Mycobacterium tuberculosis pathogenesis: potential as drug targets.Harnessing the power of transposon mutagenesis for antibacterial target identification and evaluation.Proteins released by Helicobacter pylori in vitro.Processing and maturation of the pilin of the type IV secretion system encoded within the gonococcal genetic island.Thiol redox requirements and substrate specificities of recombinant cytochrome c assembly systems II and III.Expression, purification and crystallization of a membrane-associated, catalytically active type I signal peptidase from Staphylococcus aureus.
P2860
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P2860
The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
The structure and mechanism of ...... es. A novel antibiotic target.
@ast
The structure and mechanism of ...... es. A novel antibiotic target.
@en
type
label
The structure and mechanism of ...... es. A novel antibiotic target.
@ast
The structure and mechanism of ...... es. A novel antibiotic target.
@en
prefLabel
The structure and mechanism of ...... es. A novel antibiotic target.
@ast
The structure and mechanism of ...... es. A novel antibiotic target.
@en
P2093
P1476
The structure and mechanism of ...... es. A novel antibiotic target.
@en
P2093
Strynadka NC
P356
10.1016/S0163-7258(00)00064-4
P577
2000-07-01T00:00:00Z