Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression
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Targeting Cell Survival Proteins for Cancer Cell DeathThe emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.Acid ceramidase is upregulated in AML and represents a novel therapeutic target.Vitamin D decreases STAT phosphorylation and inflammatory cytokine output in T-LGL leukemia.Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells.Attacking cancer's Achilles heel: antagonism of anti-apoptotic BCL-2 family membersAtg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model.Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products.Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner.Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML
P2860
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P2860
Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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name
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@ast
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@en
type
label
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@ast
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@en
prefLabel
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@ast
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@en
P2093
P2860
P50
P356
P1476
Maritoclax induces apoptosis i ...... with elevated Mcl-1 expression
@en
P2093
David Claxton
Kenichiro Doi
Shantu Amin
Thomas P Loughran
P2860
P304
P356
10.4161/CBT.29186
P577
2014-05-19T00:00:00Z