Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
about
Granzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence.Granzyme B-induced mitochondrial ROS are required for apoptosisHAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart.Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation.A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS.Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease.Machine learning for predicting lifespan-extending chemical compoundsNew roles for mitochondrial proteases in health, ageing and disease.Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL.Exploring the anti-apoptotic role of HAX-1 versus BCL-XL in cytokine-dependent bone marrow-derived cells from mice.Kostmann's Disease and HCLS1-Associated Protein X-1 (HAX1).4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease.HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC.IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.Amelioration of High Fructose-Induced Cardiac Hypertrophy by Naringin.
P2860
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P2860
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@ast
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@en
type
label
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@ast
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@en
prefLabel
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@ast
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@en
P2093
P2860
P356
P1476
Deregulation of mitochondrial ...... e B and direct Hax-1 cleavage.
@en
P2093
Christopher J Froelich
Hannah Rabinowich
Leslie A Goldstein
Simon C Watkins
P2860
P304
22461-22472
P356
10.1074/JBC.M109.086587
P407
P577
2010-04-13T00:00:00Z