The structure-activity relationship of urea derivatives as anti-tuberculosis agents. - Wikidata - wikimedia - TriplyDB

The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

http://www.wikidata.org/entity/Q33992683

about

New agents for the treatment of drug-resistant Mycobacterium tuberculosis Activities of N,N'-Diarylurea MMV665852 analogs against Schistosoma mansoni Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus.Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone.The tuberculosis drug discovery and development pipeline and emerging drug targets.New approaches to target the mycolic acid biosynthesis pathway for the development of tuberculosis therapeutics.A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone Antiinfectives targeting enzymes and the proton motive force.Advances in Drug Discovery and Development for Pediatric Tuberculosis.Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties.Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3 Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis.Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds In Vitro.Resistance in tuberculosis: what do we know and where can we go?Tuberculosis drug discovery and emerging targets.Design, synthesis and evaluation of indole-2-carboxamides with pan anti-mycobacterial activity.New structural classes of antituberculosis agents.Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols.Novel Sulfamethoxazole Ureas and Oxalamide as Potential Antimycobacterial Agents.Solvent-free synthesis, DNA-topoisomerase II activity and molecular docking study of new asymmetrically N,N'-substituted ureas.

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P2860

The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

http://www.wikidata.org/entity/Q33992683

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

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The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

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The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

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Christophe Morisseau

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Rebecca M Crew

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P2860

cDNA cloning and expression of a soluble epoxide hydrolase from human liver

The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis

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Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies.

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