Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole.
about
Helicobacter acinonychis: genetic and rodent infection studies of a Helicobacter pylori-like gastric pathogen of cheetahs and other big catsStructure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pyloriAspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agentsEnzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori.Point mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reductionUnexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variabilityResponse to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori.Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistanceHelicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain.Age-dependent changes in susceptibility of suckling mice to individual strains of Helicobacter pylori.Diverse phenotypes resulting from polyphosphate kinase gene (ppk1) inactivation in different strains of Helicobacter pyloriAnalysis of clinical isolates of Helicobacter pylori in Pakistan reveals high degrees of pathogenicity and high frequencies of antibiotic resistance.Mutations in the 16S rRNA genes of Helicobacter pylori mediate resistance to tetracycline.Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pyloriClostridium difficile drug pipeline: challenges in discovery and development of new agentsMolecular biology methods for the characterization of Helicobacter pylori infections and their diagnosis.Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa.Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversityAntimicrobial susceptibility of Helicobacter pylori strains isolated in BangladeshThe mutation of the rdxA gene in metronidazole-resistant Helicobacter pylori clinical isolates.Julian Davies and the discovery of kanamycin resistance transposon Tn5.Evidence for lateral transfer of genes encoding ferredoxins, nitroreductases, NADH oxidase, and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entamoeba histolytica.Emergence of tetracycline resistance in Helicobacter pylori: multiple mutational changes in 16S ribosomal DNA and other genetic loci.Molecular patchwork: Chromosomal recombination between two Helicobacter pylori strains during natural colonization.The fdxA ferredoxin gene can down-regulate frxA nitroreductase gene expression and is essential in many strains of Helicobacter pylori.The Bioinformatics Report of Mutation Outcome on NADPH Flavin Oxidoreductase Protein Sequence in Clinical Isolates of H. pylori.Emergence of high-level azithromycin resistance in Campylobacter jejuni isolates from pediatric diarrhea patients in Kolkata, India.High prevalence and level of resistance to metronidazole, but lack of resistance to other antimicrobials in Helicobacter pylori, isolated from a multiracial population in Kuwait.Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori.Evolution of Helicobacter pylori susceptibility to antibiotics during a 10-year period in Lithuania.Most Helicobacter pylori strains of Kolkata in India are resistant to metronidazole but susceptible to other drugs commonly used for eradication and ulcer therapy.Urea sensitization caused by separation of Helicobacter pylori RNA polymerase beta and beta' subunits.FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicity.
P2860
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P2860
Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@ast
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@en
type
label
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@ast
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@en
prefLabel
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@ast
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@en
P2093
P2860
P1476
Roles of FrxA and RdxA nitrore ...... d resistance to metronidazole.
@en
P2093
A K Mukhopadhyay
D Dailidiene
P S Hoffman
P2860
P304
P356
10.1128/JB.183.17.5155-5162.2001
P407
P577
2001-09-01T00:00:00Z