Transcription of the gene mediating methicillin resistance in Staphylococcus aureus (mecA) is corepressed but not coinduced by cognate mecA and beta-lactamase regulators.
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Acquired inducible antimicrobial resistance in Gram-positive bacteriaThree-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistanceOn the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operatorConformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against -lactam antibioticsStructural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent EndopeptidaseExposure of clinical MRSA heterogeneous strains to β-lactams redirects metabolism to optimize energy production through the TCA cycleEvidence of an intramolecular interaction between the two domains of the BlaR1 penicillin receptor during the signal transduction.Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons.Methicillin-resistance in Staphylococcus aureus is not affected by the overexpression in trans of the mecA gene repressor: a surprising observation.A peptidoglycan fragment triggers β-lactam resistance in Bacillus licheniformisBacillus licheniformis BlaR1 L3 loop is a zinc metalloprotease activated by self-proteolysis.The anti-repressor MecR2 promotes the proteolysis of the mecA repressor and enables optimal expression of β-lactam resistance in MRSA.Redefining the role of the β-lactamase locus in methicillin-resistant Staphylococcus aureus: β-lactamase regulators disrupt the MecI-mediated strong repression on mecA and optimize the phenotypic expression of resistance in strains with constitutivemecA-blaZ corepressors in clinical Staphylococcus aureus isolatesImproved oxacillin treatment outcomes in experimental skin and lung infection by a methicillin-resistant Staphylococcus aureus isolate with a vraSR operon deletionQuantitation of mecA transcription in oxacillin-resistant Staphylococcus aureus clinical isolatesCo-blockade of mecR1/blaR1 signal pathway to restore antibiotic susceptibility in clinical isolates of methicillin-resistant Staphylococcus aureus.Whole-genome analysis of an oxacillin-susceptible CC80 mecA-positive Staphylococcus aureus clinical isolate: insights into the mechanisms of cryptic methicillin resistance.Identification and phenotypic characterization of a beta-lactam-dependent, methicillin-resistant Staphylococcus aureus strainJumping the barrier to beta-lactam resistance in Staphylococcus aureus.A comparative study for the inactivation of multidrug resistance bacteria using dielectric barrier discharge and nano-second pulsed plasma.Broadening the spectrum of β-lactam antibiotics through inhibition of signal peptidase type I.Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec.Modes and modulations of antibiotic resistance gene expression.Development of homogeneous expression of resistance in methicillin-resistant Staphylococcus aureus clinical strains is functionally associated with a beta-lactam-mediated SOS response.Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.Role of the mecA gene in oxacillin resistance in a Staphylococcus aureus clinical strain with a pvl-positive ST59 genetic background.Antimicrobial susceptibility testing: a primer for clinicians.Regulation of the expression of the β-lactam antibiotic-resistance determinants in methicillin-resistant Staphylococcus aureus (MRSA).Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.Staphylococcus aureus PBP4 is essential for beta-lactam resistance in community-acquired methicillin-resistant strains.ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis.Antibiotic resistance in Staphylococcus aureus. Current status and future prospects.Role of the Stringent Stress Response in the Antibiotic Resistance Phenotype of Methicillin-Resistant Staphylococcus aureus.Identification in methicillin-susceptible Staphylococcus hominis of an active primordial mobile genetic element for the staphylococcal cassette chromosome mec of methicillin-resistant Staphylococcus aureus.Novel polymorphisms in mec genes and a new mec complex type in methicillin-resistant Staphylococcus aureus isolates obtained in rural Wisconsin.Synergy of daptomycin with oxacillin and other beta-lactams against methicillin-resistant Staphylococcus aureusBD Phoenix and Vitek 2 detection of mecA-mediated resistance in Staphylococcus aureus with cefoxitin.Lack of relationship between purine biosynthesis and vancomycin resistance in Staphylococcus aureus: a cautionary tale for microarray interpretation.Novel methicillin resistance gene mecD in clinical Macrococcus caseolyticus strains from bovine and canine sources.
P2860
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P2860
Transcription of the gene mediating methicillin resistance in Staphylococcus aureus (mecA) is corepressed but not coinduced by cognate mecA and beta-lactamase regulators.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Transcription of the gene medi ...... and beta-lactamase regulators.
@ast
Transcription of the gene medi ...... and beta-lactamase regulators.
@en
type
label
Transcription of the gene medi ...... and beta-lactamase regulators.
@ast
Transcription of the gene medi ...... and beta-lactamase regulators.
@en
prefLabel
Transcription of the gene medi ...... and beta-lactamase regulators.
@ast
Transcription of the gene medi ...... and beta-lactamase regulators.
@en
P2093
P2860
P1476
Transcription of the gene medi ...... and beta-lactamase regulators.
@en
P2093
G L Archer
T K McKinney
V K Sharma
P2860
P304
P356
10.1128/JB.183.23.6862-6868.2001
P407
P577
2001-12-01T00:00:00Z