HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems.
about
Engineered IgG1-Fc--one fragment to bind them allDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicityCharacterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodiesSynthetic approach to the generation of antibody diversityThe selection performance of an antibody library displayed on filamentous phage coat proteins p9, p3 and truncated p3Hapten mediated display and pairing of recombinant antibodies accelerates assay assembly for biothreat countermeasuresA fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties.Ebolavirus nucleoprotein C-termini potently attract single domain antibodies enabling monoclonal affinity reagent sandwich assay (MARSA) formulation.An improved single-chain Fab platform for efficient display and recombinant expression.One-step zero-background IgG reformatting of phage-displayed antibody fragments enabling rapid and high-throughput lead identification.Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potentialHigh-affinity recombinant antibody fragments (Fabs) can be applied in peptide enrichment immuno-MRM assays.Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy.Progress in the development of immunoanalytical methods incorporating recombinant antibodies to small molecular weight biotoxins.Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigensHigh-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin DomainsA Novel Human scFv Library with Non-Combinatorial Synthetic CDR Diversity.Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.A Recombinant Positive Control for Serology Diagnostic Tests Supporting Elimination of Onchocerca volvulus7th annual European Antibody Congress 2011: November 29-December 1, 2011, Geneva, Switzerland.NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle.Construction of a scFv Library with Synthetic, Non-combinatorial CDR Diversity.Generating Conformation and Complex-Specific Synthetic Antibodies.High-Throughput IgG Conversion of Phage Displayed Fab Antibody Fragments by AmplYFast.Natural and man-made V-gene repertoires for antibody discovery.In vivo characterization of the novel CD44v6-targeting Fab fragment AbD15179 for molecular imaging of squamous cell carcinoma: a dual-isotope study.Monoclonal antibodies: technologies for early discovery and engineering.Phage display-derived human antibodies in clinical development and therapyAn automated immunoassay for early specificity profiling of antibodiesDegradation of C-terminal tag sequences on domain antibodies purified from E. coli supernatant.Nonspecificity in a nonimmune human scFv repertoire.8(th) Annual European Antibody Congress 2012: November 27-28, 2012, Geneva, Switzerland.CD44v6-Targeted Imaging of Head and Neck Squamous Cell Carcinoma: Antibody-Based Approaches.A novel Fc-engineered human ICAM-1/CD54 antibody with potent anti-myeloma activity developed by cellular panning of phage display libraries.Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein.Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries.Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy.Antibody Phage Display
P2860
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P2860
HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@ast
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@en
type
label
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@ast
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@en
prefLabel
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@ast
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@en
P2093
P1476
HuCAL PLATINUM, a synthetic Fa ...... mammalian expression systems.
@en
P2093
Andrea Polzer
Andreas Popp
Catrin Pracht
Johanna Kölln
Josef Prassler
Marion Bauer
Markus Enzelberger
Solveig Peters
Stefanie Thiel
Stefanie Urlinger
P304
P356
10.1016/J.JMB.2011.08.012
P407
P577
2011-08-12T00:00:00Z