DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. - Wikidata - wikimedia - TriplyDB

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

http://www.wikidata.org/entity/Q34001042

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An overview of epigenetics and chemoprevention Combating the epigenome: epigenetic drugs against non-Hodgkin's lymphoma Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation Inactive DNMT3B splice variants modulate de novo DNA methylation Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia.Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells Genomic insights into cancer-associated aberrant CpG island hypermethylation DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation.Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis.Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells BIX-01294 treatment blocks cell proliferation, migration and contractility in ovine foetal pulmonary arterial smooth muscle cells.Perspectives and future directions for epigenetics in hematology.Valproic acid shows a potent antitumor effect with alteration of DNA methylation in neuroblastoma Role of histone deacetylases in regulation of phenotype of ovine newborn pulmonary arterial smooth muscle cells.Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer.An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma.Epigenetics and B-cell lymphoma.Epigenetics of myelodysplastic syndromes.Regulation of ribosomal gene expression in cancer.Epigenetics in T-cell acute lymphoblastic leukemia.Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.Genetic Studies on Mammalian DNA Methyltransferases.Splice variants DNMT3B4 and DNMT3B7 overexpression inhibit cell proliferation in 293A cell line.Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.DNMT3B gene amplification predicts resistance to DNA demethylating drugs.Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis.DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma.Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.Aberrant DNMT3B7 expression correlates to tissue type, stage, and survival across cancers

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P2860

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

http://www.wikidata.org/entity/Q34001042

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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DNMT3B7, a truncated DNMT3B is ...... d accelerates lymphomagenesis.

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DNMT3B7, a truncated DNMT3B is ...... d accelerates lymphomagenesis.

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DNMT3B7, a truncated DNMT3B is ...... d accelerates lymphomagenesis.

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DNMT3B7, a truncated DNMT3B is ...... d accelerates lymphomagenesis.

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0008-5472.CAN-10-0847

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Cancer Research

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DNMT3B7, a truncated DNMT3B is ...... nd accelerates lymphomagenesis

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Anna Kamp

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Aparna Vasanthakumar

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Ari Melnick

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Christopher Hendrick

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Elizabeth M Davis

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Ivan P Moskowitz

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John Anastasi

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Kelly R Ostler

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Lucy A Godley

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Michelle M Le Beau

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P2860

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

Myc represses transcription through recruitment of DNA methyltransferase corepressor

Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

Aberrant RNA splicing and its functional consequences in cancer cells

Comparative isoschizomer profiling of cytosine methylation: the HELP assay

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

The epigenomics of cancer

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10.1158/0008-5472.CAN-10-0847

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Maria E Figueroa

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