about
What can we learn from fitness landscapes?The causes of epistasisIdentifying selection in the within-host evolution of influenza using viral sequence dataRecombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1Strong Selection Significantly Increases Epistatic Interactions in the Long-Term Evolution of a ProteinRate of adaptation in sexuals and asexuals: a solvable model of the Fisher-Muller effect.Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin.Exploring the complexity of the HIV-1 fitness landscape.The effect of bacterial recombination on adaptation on fitness landscapes with limited peak accessibilityReplaying the tape of life: quantification of the predictability of evolution.Designing antibiotic cycling strategies by determining and understanding local adaptive landscapes.Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter.Should evolutionary geneticists worry about higher-order epistasis?Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes.Properties of selected mutations and genotypic landscapes under Fisher's geometric model.Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations.The changing geometry of a fitness landscape along an adaptive walkBiophysical fitness landscapes for transcription factor binding sitesQuantifying the role of population subdivision in evolution on rugged fitness landscapes.Multidimensional epistasis and the transitory advantage of sex.Beyond the Hypercube: Evolutionary Accessibility of Fitness Landscapes with Realistic Mutational Networks.Running loose or getting lost: how HIV-1 counters and capitalizes on APOBEC3-induced mutagenesis through its Vif proteinPredictability of evolution depends nonmonotonically on population sizeAdaptation in protein fitness landscapes is facilitated by indirect pathsGenonets server-a web server for the construction, analysis and visualization of genotype networks.How Good Are Statistical Models at Approximating Complex Fitness Landscapes?Epistasis and Pleiotropy Affect the Modularity of the Genotype-Phenotype Map of Cross-Resistance in HIV-1On the (un)predictability of a large intragenic fitness landscape.Synthetic approaches to understanding biological constraints.Empirical fitness landscapes and the predictability of evolution.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Genotypic Complexity of Fisher's Geometric Model.Epistasis and the Evolution of Antimicrobial Resistance.The impact of high-order epistasis in the within-host fitness of a positive-sense plant RNA virus.Expected Effect of Deleterious Mutations on Within-Host Adaptation of Pathogens.Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus.Patterns of Epistasis between beneficial mutations in an antibiotic resistance gene.Adaptation in tunably rugged fitness landscapes: the rough Mount Fuji model.Next generation genetics.Parallelism in adaptive radiations of experimental Escherichia coli populations.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Evolutionary accessibility of mutational pathways
@ast
Evolutionary accessibility of mutational pathways
@en
Evolutionary accessibility of mutational pathways
@nl
type
label
Evolutionary accessibility of mutational pathways
@ast
Evolutionary accessibility of mutational pathways
@en
Evolutionary accessibility of mutational pathways
@nl
prefLabel
Evolutionary accessibility of mutational pathways
@ast
Evolutionary accessibility of mutational pathways
@en
Evolutionary accessibility of mutational pathways
@nl
P2093
P2860
P1476
Evolutionary accessibility of mutational pathways
@en
P2093
Alexander Klözer
J Arjan G M de Visser
Jasper Franke
Joachim Krug
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002134
P577
2011-08-18T00:00:00Z