Effects of the antibiotics netropsin and distamycin A on the structure and function of nucleic acids.
about
Minor groove binder distamycin remodels chromatin but inhibits transcriptionRecent Advances in Developing Small Molecules Targeting Nucleic AcidActivity of Hoechst 33258 against Pneumocystis carinii f. sp. muris, Candida albicans, and Candida dubliniensis.Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4).The molecular origin of DNA-drug specificity in netropsin and distamycin.Effect of DNA groove binder distamycin A upon chromatin structure.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Netropsin-poly(dA-dT) complex in solution: structure and dynamics of antibiotic-free base pair regions and those centered on bound netropsin.Systematic punctuation of eukaryotic DNA by A+T-rich sequences.The solvation contribution to the binding energy of DNA with non-intercalating antibiotics.Calorimetric and spectroscopic investigation of drug-DNA interactions. I. The binding of netropsin to poly d(AT).Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071.The molecular electrostatic potential and steric accessibility of A-DNAInteractions of DNA binding ligands with PNA-DNA hybridsSequence specific molecular recognition by a monocationic lexitropsin of the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studiesA comparison of the structure of echinomycin and triostin A complexed to a DNA fragment.Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).Antibiotic-DNA interactions: intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution.Mutual interaction between adjacent dG . dC actinomycin binding sites and dA . dT netropsin binding sites on the self-complementary d(C-G-C-G-A-A-T-T-C-G-C-G) duplex in solutionMelting thermodynamics of reversible DNA/ligand complexes at interfaces.DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove.Effect of netropsin on the derepression of enzymes during growth and sporulation of Bacillus subtilis.Left-handed Z-DNA in bands of acid-fixed polytene chromosomesExcision of pyrimidine dimers from nuclear deoxyribonucleic acid in ultraviolet-irradiated Dictyostelium discoideum.Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II).Sequence specificity of actinomycin D and Netropsin binding to pBR322 DNA analyzed by protection from DNase I.Binding to the DNA minor groove by heterocyclic dications: from AT-specific monomers to GC recognition with dimers.Interactions of nucleic acids with distamycins. Binding of Dst-3 to d(CGTTTAAACG)2 and d(CGTACGTACG)2.The effect of several nucleic acid binding drugs on the cleavage of d(GGAATTCC) and pBR 322 by the Eco RI restriction endonuclease.Duplex structure formation between oligo(dA)'s and oligo(dT)'s generated by thymine-specific interaction with netropsinDNA structure and perturbation by drug bindingMechanochemical study of NaDNA and NaDNA-netropsin fibers in ethanol-water and trifluoroethanol-water solutionsInfrared linear dichroism studies of DNA-drug complexes: quantitative determination of the drug-induced restriction of the B-A transition.The formation of A-DNA in NaDNA films is suppressed by netropsin.Infrared linear dichroism of oriented DNA-ligand complexes prepared with the wet-spinning method.Differential stabilization by netropsin of inducible B-like conformations in deoxyribo-, ribo- and 2'-deoxy-2'-fluororibo-adenosine containing duplexes of (dA)n . (dT)n and (dA)n . (dU)na.Specific interaction of netropsin, distamycin-3 and analogs with LC duplexes: reversion towards the B form of the 2'-deoxy-.2'-deoxy-2'-fluoro-hybrid duplexes upon specific interaction with netropsin, distamycin-3 and analogs.Protection of (dA.dT) cluster regions in the DNAase I cleavage of DNA by specific interaction with netropsin.
P2860
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P2860
Effects of the antibiotics netropsin and distamycin A on the structure and function of nucleic acids.
description
1975 nî lūn-bûn
@nan
1975 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1975 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1975年の論文
@ja
1975年論文
@yue
1975年論文
@zh-hant
1975年論文
@zh-hk
1975年論文
@zh-mo
1975年論文
@zh-tw
1975年论文
@wuu
name
Effects of the antibiotics net ...... and function of nucleic acids.
@ast
Effects of the antibiotics net ...... and function of nucleic acids.
@en
Effects of the antibiotics net ...... and function of nucleic acids.
@nl
type
label
Effects of the antibiotics net ...... and function of nucleic acids.
@ast
Effects of the antibiotics net ...... and function of nucleic acids.
@en
Effects of the antibiotics net ...... and function of nucleic acids.
@nl
prefLabel
Effects of the antibiotics net ...... and function of nucleic acids.
@ast
Effects of the antibiotics net ...... and function of nucleic acids.
@en
Effects of the antibiotics net ...... and function of nucleic acids.
@nl
P1476
Effects of the antibiotics net ...... and function of nucleic acids.
@en
P2093
P304
P577
1975-01-01T00:00:00Z