Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins.
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Clostridium difficile toxins: mechanism of action and role in disease.Physiology and function of the tight junction.SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cellsIntestinal epithelial restitution after TcdB challenge and recovery from Clostridium difficile infection in mice with alanyl-glutamine treatment.Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control.Role of retinol in protecting epithelial cell damage induced by Clostridium difficile toxin A.Expression of recombinant Clostridium difficile toxin A and B in Bacillus megateriumClostridium difficile toxin B activates dual caspase-dependent and caspase-independent apoptosis in intoxicated cells.Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxinMonocytes are highly sensitive to clostridium difficile toxin A-induced apoptotic and nonapoptotic cell deathA protein kinase A-dependent mechanism by which rotavirus affects the distribution and mRNA level of the functional tight junction-associated protein, occludin, in human differentiated intestinal Caco-2 cells.New model for studying the migration of immune cells into intestinal epithelial cell monolayers.The intestinal spirochete Brachyspira pilosicoli attaches to cultured Caco-2 cells and induces pathological changes.Vibrio parahaemolyticus disruption of epithelial cell tight junctions occurs independently of toxin production.Lactobacillus rhamnosus L34 and Lactobacillus casei L39 suppress Clostridium difficile-induced IL-8 production by colonic epithelial cellsA comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.Bio-physical characteristics of gastrointestinal mucosa of celiac patients: comparison with control subjects and effect of gluten free diet-Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease.Bacterial factors exploit eukaryotic Rho GTPase signaling cascades to promote invasion and proliferation within their host.Role of the host defense system and intestinal microbial flora in the pathogenesis of necrotizing enterocolitis.Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex.Escherichia coli STb enterotoxin dislodges claudin-1 from epithelial tight junctions.Vaccine-induced intestinal immunity to ricin toxin in the absence of secretory IgA.Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice.Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury.Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis.Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment.Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection.Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation.Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cellsIdentification of a novel virulence factor in Clostridium difficile that modulates toxin sensitivity of cultured epithelial cells.Impenetrable barriers or entry portals? The role of cell-cell adhesion during infectionBreaking into the epithelial apical-junctional complex--news from pathogen hackersProteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability.Synapses: sites of cell recognition, adhesion, and functional specification.Astrovirus increases epithelial barrier permeability independently of viral replicationAdvances in nasal drug delivery through tight junction technology.The basolateral vesicle sorting machinery and basolateral proteins are recruited to the site of enteropathogenic E. coli microcolony growth at the apical membrane.Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system
P2860
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P2860
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Clostridium difficile toxins d ...... on of tight junction proteins.
@ast
Clostridium difficile toxins d ...... on of tight junction proteins.
@en
Clostridium difficile toxins d ...... on of tight junction proteins.
@nl
type
label
Clostridium difficile toxins d ...... on of tight junction proteins.
@ast
Clostridium difficile toxins d ...... on of tight junction proteins.
@en
Clostridium difficile toxins d ...... on of tight junction proteins.
@nl
prefLabel
Clostridium difficile toxins d ...... on of tight junction proteins.
@ast
Clostridium difficile toxins d ...... on of tight junction proteins.
@en
Clostridium difficile toxins d ...... on of tight junction proteins.
@nl
P2093
P2860
P1476
Clostridium difficile toxins d ...... on of tight junction proteins.
@en
P2093
C A Parkos
C von Eichel-Streiber
J L Madara
J R Turner
P2860
P304
P356
10.1128/IAI.69.3.1329-1336.2001
P407
P577
2001-03-01T00:00:00Z