Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells.
about
Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibitionCytotoxic metabolites from an Indonesian sponge Lendenfeldia spIsocudraxanthone K induces growth inhibition and apoptosis in oral cancer cells via hypoxia inducible factor-1α.Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells.Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors.Sodwanone and yardenone triterpenes from a South African species of the marine sponge Axinella inhibit hypoxia-inducible factor-1 (HIF-1) activation in both breast and prostate tumor cellsHypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions.Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines.Molecular-targeted antitumor agents. 15. Neolamellarins from the marine sponge Dendrilla nigra inhibit hypoxia-inducible factor-1 activation and secreted vascular endothelial growth factor production in breast tumor cells.Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration.TSC2 deficiency increases PTEN via HIF1alphaEDL-360: A Potential Novel Antiglioma Agent.Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma.Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses.Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathwaysCripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).HIF inhibitors for ischemic retinopathies and cancers: options beyond anti-VEGF therapies.Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cellsCatalytic mechanism of aromatic prenylation by NphB.Natural compounds regulate glycolysis in hypoxic tumor microenvironment.
P2860
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P2860
Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@ast
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@en
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@nl
type
label
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@ast
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@en
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@nl
prefLabel
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@ast
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@en
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@nl
P2093
P2860
P921
P356
P1476
Terpenoid tetrahydroisoquinoli ...... actor-1 in breast tumor cells.
@en
P2093
D Chuck Dunbar
Dale G Nagle
Deborah K Jones
Ilias Muhammad
Kaleem Asjad Mohammed
Yong-Pil Kim
Yu-Dong Zhou
P2860
P304
P356
10.1021/NP050029M
P577
2005-06-01T00:00:00Z