A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans.
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Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1A single amino acid substitution in the group 1 Trypanosoma brucei gambiense haptoglobin-hemoglobin receptor abolishes TLF-1 bindingC-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesienseStructure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunityCrystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infectionsThe apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactionsHydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomesImmune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to PathogenicityHow Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?Trypanosome resistance to human innate immunity: targeting Achilles' heelStructure of the haptoglobin-haemoglobin complexStructural basis for trypanosomal haem acquisition and susceptibility to the host innate immune systemCytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damageGenetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug targetTrypanosoma brucei gambiense group 1 is distinguished by a unique amino acid substitution in the HpHb receptor implicated in human serum resistanceCathepsin-L can resist lysis by human serum in Trypanosoma brucei bruceiSpecific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated EndocytosisTrypanosoma evansi and surra: a review and perspectives on transmission, epidemiology and control, impact, and zoonotic aspectsHeme pathway evolution in kinetoplastid protistsThree-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomographyMembrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes.Motility and more: the flagellum of Trypanosoma brucei.Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasisTrypanosome lytic factor, an antimicrobial high-density lipoprotein, ameliorates Leishmania infection.Identification of copy number variants defining genomic differences among major human groupsEvidence that low endocytic activity is not directly responsible for human serum resistance in the insect form of African trypanosomesEvolution of the primate trypanolytic factor APOL1Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children.Cellular and molecular remodeling of the endocytic pathway during differentiation of Trypanosoma brucei bloodstream forms.Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor.A retained secretory signal peptide mediates high density lipoprotein (HDL) assembly and function of haptoglobin-related protein.Taste for blood: hemoglobin as a nutrient source for pathogens.Cell biology of the trypanosome genome.Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin.Make it, take it, or leave it: heme metabolism of parasites.High density lipoprotein: it's not just about lipid transport anymoreA cell-surface phylome for African trypanosomes.The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense.Late endosomal Rab7 regulates lysosomal trafficking of endocytic but not biosynthetic cargo in Trypanosoma brucei.
P2860
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P2860
A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@ast
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@en
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@nl
type
label
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@ast
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@en
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@nl
prefLabel
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@ast
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@en
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@nl
P2093
P50
P356
P1433
P1476
A haptoglobin-hemoglobin recep ...... Trypanosoma brucei in humans.
@en
P2093
Annette Pays
Géraldine De Muylder
Marianne J Nielsen
Patricia Tebabi
P304
P356
10.1126/SCIENCE.1156296
P407
P577
2008-05-01T00:00:00Z