Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth
about
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heartAbr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.Sec14 homology domain targets p50RhoGAP to endosomes and provides a link between Rab and Rho GTPasesRho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition.P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells.Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization.The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain.Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts.Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypesRho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment.Increased hematopoietic stem cell mobilization in aged mice.Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A.Cdc42GAP, reactive oxygen species, and the vimentin networkInhibition and termination of physiological responses by GTPase activating proteins.Functional plasticity of the BNIP-2 and Cdc42GAP Homology (BCH) domain in cell signaling and cell dynamics.Atg13 Is Essential for Autophagy and Cardiac Development in Mice.Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells.Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3.Mammalian diseases of phosphatidylinositol transfer proteins and their homologs.
P2860
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P2860
Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@ast
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@en
Cdc42GAP regulates c-Jun N-terminal kinase
@nl
type
label
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@ast
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@en
Cdc42GAP regulates c-Jun N-terminal kinase
@nl
prefLabel
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@ast
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@en
Cdc42GAP regulates c-Jun N-terminal kinase
@nl
P2093
P2860
P356
P1476
Cdc42GAP regulates c-Jun N-ter ...... ing mammalian perinatal growth
@en
P2093
Chia-Yi Kuan
Kevin Burns
Linda Yang
P2860
P304
13484-13489
P356
10.1073/PNAS.0504420102
P407
P577
2005-09-12T00:00:00Z