Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis. - Wikidata - wikimedia - TriplyDB

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.

http://www.wikidata.org/entity/Q34016565

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Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells Pathophysiology of hereditary hemochromatosis Evidence for a sequential transfer of iron amongst ferritin, transferrin and transferrin receptor during duodenal absorption of iron in rat and human Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis Targeting therapeutics across the blood brain barrier (BBB), prerequisite towards thrombolytic therapy for cerebrovascular disorders-an overview and advancements Redox control of prion and disease pathogenesis.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.Intracellular iron transport and storage: from molecular mechanisms to health implications.The hemochromatosis protein HFE inhibits iron export from macrophages.Normal iron metabolism and the pathophysiology of iron overload disorders Molecular pathogenesis of iron overload.Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.Review article: haemochromatosis.Molecular mechanisms and regulation of iron transport.Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation.HFE gene in primary and secondary hepatic iron overload.The regulation of cellular iron metabolism.Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages The role of Hfe in transferrin-bound iron uptake by hepatocytes.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system Differential effects of basolateral and apical iron supply on iron transport in Caco-2 cells.Detection of intracellular iron by its regulatory effect.The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin.Increased susceptibility to Mycobacterium avium in hemochromatosis protein HFE-deficient mice.The prevalence of HFE C282Y gene mutation is increased in Spanish patients with porphyria cutanea tarda without hepatitis C virus infection.HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface.

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P2860

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.

http://www.wikidata.org/entity/Q34016565

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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Proceedings of the National Academy of Sciences of the United States of America

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Regulation of transferrin-medi ...... in hereditary hemochromatosis.

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P2093

Abdul Waheed

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Bruce R Bacon

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Jeffrey H Grubb

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Mark E Costaldi

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Robert E Fleming

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Robert S Britton

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Shunji Tomatsu

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William S Sly

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Xiao Yan Zhou

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P2860

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Efficient selection for high-expression transfectants with a novel eukaryotic vector

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