Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.
about
Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cellsPathophysiology of hereditary hemochromatosisEvidence for a sequential transfer of iron amongst ferritin, transferrin and transferrin receptor during duodenal absorption of iron in rat and humanEnhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasisTargeting therapeutics across the blood brain barrier (BBB), prerequisite towards thrombolytic therapy for cerebrovascular disorders-an overview and advancementsRedox control of prion and disease pathogenesis.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's diseaseIron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.Intracellular iron transport and storage: from molecular mechanisms to health implications.The hemochromatosis protein HFE inhibits iron export from macrophages.Normal iron metabolism and the pathophysiology of iron overload disordersMolecular pathogenesis of iron overload.Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.Review article: haemochromatosis.Molecular mechanisms and regulation of iron transport.Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation.HFE gene in primary and secondary hepatic iron overload.The regulation of cellular iron metabolism.Decreased ferroportin promotes myeloma cell growth and osteoclast differentiationMetal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and MacrophagesThe role of Hfe in transferrin-bound iron uptake by hepatocytes.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune systemDifferential effects of basolateral and apical iron supply on iron transport in Caco-2 cells.Detection of intracellular iron by its regulatory effect.The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin.Increased susceptibility to Mycobacterium avium in hemochromatosis protein HFE-deficient mice.The prevalence of HFE C282Y gene mutation is increased in Spanish patients with porphyria cutanea tarda without hepatitis C virus infection.HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface.
P2860
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P2860
Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@ast
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@en
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@nl
type
label
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@ast
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@en
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@nl
prefLabel
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@ast
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@en
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@nl
P2093
P2860
P356
P1476
Regulation of transferrin-medi ...... in hereditary hemochromatosis.
@en
P2093
Abdul Waheed
Bruce R Bacon
Jeffrey H Grubb
Mark E Costaldi
Robert E Fleming
Robert S Britton
Shunji Tomatsu
William S Sly
Xiao Yan Zhou
P2860
P304
P356
10.1073/PNAS.042701499
P407
P577
2002-02-26T00:00:00Z