EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
about
Estrogen receptor alpha gene amplification in breast cancer: 25 years of debateSingle-cell analysis tools for drug discovery and developmentIntra-tumor heterogeneity of cancer cells and its implications for cancer treatmentAdvances and applications of single-cell sequencing technologiesHeterogeneity of epidermal growth factor receptor signalling networks in glioblastomaChromothripsis from DNA damage in micronuclei.Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis.NGSCheckMate: software for validating sample identity in next-generation sequencing studies within and across data types.Greater than the sum of its parts: single-nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBM.Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolutionOptimizing sparse sequencing of single cells for highly multiplex copy number profilingCalibrating genomic and allelic coverage bias in single-cell sequencing.Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion.FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development.A wide spectrum of EGFR mutations in glioblastoma is detected by a single clinical oncology targeted next-generation sequencing panelClinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomasGenetic Testing and Tissue Banking for Personalized Oncology: Analytical and Institutional Factors.CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion.Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6Rapid Intraoperative Molecular Characterization of Glioma.Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes.Advances in Immunotherapy for Glioblastoma Multiforme.Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq.Molecular pathologic diagnosis of epidermal growth factor receptor.Advances and challenges in the molecular biology and treatment of glioblastoma-is there any hope for the future?Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma MultiformeReACT Phase II trial: a critical evaluation of the use of rindopepimut plus bevacizumab to treat EGFRvIII-positive recurrent glioblastoma.Molecular profiling of gliomas: potential therapeutic implications.Emerging circulating biomarkers in glioblastoma: promises and challenges.Glioblastoma targeted therapy: updated approaches from recent biological insights.Implications of mitogen-activated protein kinase signaling in glioma.New library construction method for single-cell genomes.Antibody-drug conjugates in glioblastoma therapy: the right drugs to the right cells.EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.
P2860
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P2860
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@ast
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@en
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@nl
type
label
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@ast
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@en
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@nl
prefLabel
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@ast
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@en
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@nl
P2093
P2860
P1433
P1476
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
@en
P2093
Azra H Ligon
Brendan Blumenstiel
Cecile L Maire
Cheng-Zhong Zhang
Heather Homer
J Christopher Love
Joonil Jung
Joshua M Francis
Keith L Ligon
Sam Haidar
P2860
P304
P356
10.1158/2159-8290.CD-13-0879
P577
2014-06-03T00:00:00Z