about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesEssential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesisDlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligasesUTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activityX-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionUTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental programBloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screeningCul4B regulates neural progenitor cell growth.Chromatin and oxygen sensing in the context of JmjC histone demethylasesDeletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferationLack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.Histone lysine demethylases in mammalian embryonic development.Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndromeA Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 UbiquitylationPathogenic Role of the CRL4 Ubiquitin Ligase in Human DiseaseCUL4B ubiquitin ligase in mouse development: a model for human X-linked mental retardation syndrome?Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm.Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons.Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian EmbryosHigh-throughput discovery of novel developmental phenotypes.FGF treatment of host embryos injected with ES cells increases rates of chimaerism.Large-scale mouse knockouts and phenotypes.Histone lysine demethylases as targets for anticancer therapy.Jumonji family histone demethylases in neural development.Mitochondrial one-carbon metabolism and neural tube defects.Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.An in vivo requirement for the mediator subunit med14 in the maintenance of stem cell populations.Evolution of the Discs large gene family provides new insights into the establishment of apical epithelial polarity and the etiology of mental retardation.Mutations in Lyar and p53 are synergistically lethal in female mice.CXorf56, a dendritic neuronal protein, identified as a new candidate gene for X-linked intellectual disability.A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.JARID1 Histone Demethylases: Emerging Targets in Cancer.Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.Steuerungsmechanismen der Entodermentwicklung in der Maus
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phenotypic annotation of the mouse X chromosome
@ast
Phenotypic annotation of the mouse X chromosome
@en
Phenotypic annotation of the mouse X chromosome
@nl
type
label
Phenotypic annotation of the mouse X chromosome
@ast
Phenotypic annotation of the mouse X chromosome
@en
Phenotypic annotation of the mouse X chromosome
@nl
prefLabel
Phenotypic annotation of the mouse X chromosome
@ast
Phenotypic annotation of the mouse X chromosome
@en
Phenotypic annotation of the mouse X chromosome
@nl
P2093
P2860
P50
P356
P1433
P1476
Phenotypic annotation of the mouse X chromosome
@en
P2093
Brian J Cox
Claude van Campenhout
Heiko Lickert
Marion Vollmer
Owen Tamplin
Thomas Floss
Wolfgang Wurst
P2860
P304
P356
10.1101/GR.105106.110
P577
2010-06-14T00:00:00Z