Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital. - Wikidata - wikimedia - TriplyDB

Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.

Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.

http://www.wikidata.org/entity/Q34026277

about

Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2 Diagnostic methods and treatment options for focal cortical dysplasia A randomised controlled trial of bumetanide in the treatment of autism in children Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transporters Acute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemia Optogenetic activation of septal GABAergic afferents entrains neuronal firing in the medial habenula Short-Term Effects of Phenobarbitone on Electrographic Seizures in Neonates.Low-frequency stimulation of the primary focus retards positive transfer of secondary focus.The Subiculum: A Potential Site of Ictogenesis in a Neonatal Seizure Model.Effects of bumetanide on neurobehavioral function in children and adolescents with autism spectrum disorders.Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring.Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn Seizures Subunit composition of neurotransmitter receptors in the immature and in the epileptic brain.Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures Cation-chloride cotransporters in neuronal development, plasticity and disease Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis.Carts, Horses, and Push-Pull Regulation of EGABA in Neonatal Seizures Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever!The effect of bumetanide treatment on the sensory behaviours of a young girl with Asperger syndrome.GABAergic depolarization during early cortical development and implications for anticonvulsive therapy in neonates.Excitatory action of GABA on immature neurons is not due to absence of ketone bodies metabolites or other energy substrates.Is it safe to use a diuretic to treat seizures early in development ?Blocking seizures with the diuretic bumetanide: promises and pitfalls.Timing of developmental sequences in different brain structures: physiological and pathological implications.Cortical inhibition, pH and cell excitability in epilepsy: what are optimal targets for antiepileptic interventions?Depolarizing GABA and developmental epilepsies.GABAergic Synchronization in Epilepsy.Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus.Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus.Treating Fragile X syndrome with the diuretic bumetanide: a case report.A novel prodrug-based strategy to increase effects of bumetanide in epilepsy.Improving emotional face perception in autism with diuretic bumetanide: a proof-of-concept behavioral and functional brain imaging pilot study.GABAergic signalling in a neurogenic niche of the turtle spinal cord.The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition.

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P2860

Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.

http://www.wikidata.org/entity/Q34026277

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Neuronal chloride accumulation ...... m activities by phenobarbital.

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Neuronal chloride accumulation ...... rm activities by phenobarbital

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P2093

Asma Bhar

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Geneviève Chazal

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Nadine Ferrand

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Olivier Dulac

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Romain Nardou

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Sumii Yamamoto

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P2860

Mice with a targeted disruption of the Cl-/HCO3- exchanger AE3 display a reduced seizure threshold

Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII

GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations

NKCC1 transporter facilitates seizures in the developing brain

Excitatory effect of GABAergic axo-axonic cells in cortical microcircuits

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability

Subunit-specific trafficking of GABA(A) receptors during status epilepticus

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987-1002

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scholarly article

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10.1093/BRAIN/AWR041

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P433

Pt 4

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134

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Yehezkel Ben-Ari

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2011-03-23T00:00:00Z

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50850524

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21436113

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