Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
about
IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaIDH mutations in tumorigenesis and their potential role as novel therapeutic targets.Isocitrate dehydrogenase from Streptococcus mutans: biochemical properties and evaluation of a putative phosphorylation site at Ser102Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases.Prognostic value of isocitrate dehydrogenase mutations in myelodysplastic syndromes: a retrospective cohort study and meta-analysis.Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2.Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanomaBiochemical characterization of NADP⁺-dependent isocitrate dehydrogenase from Microcystis aeruginosa PCC7806.A unique four-hub protein cluster associates to glioblastoma progression.Identification of ovarian cancer subtype-specific network modules and candidate drivers through an integrative genomics approach.What do we know about IDH1/2 mutations so far, and how do we use it?Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.Mitochondrial Dysfunction in Gliomas: Pharmacotherapeutic Potential of Natural Compounds.Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.Emerging insights into barriers to effective brain tumor therapeutics.Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant Glioma.HOT mutation screening in human glioblastomas.Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming.Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients.Metabolic Reprogramming in Glioma.Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight.The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells.WEE1 epigenetically modulates 5-hmC levels by pY37-H2B dependent regulation of IDH2 gene expression.Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era.
P2860
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P2860
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@ast
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@en
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@nl
type
label
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@ast
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@en
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@nl
prefLabel
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@ast
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@en
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@nl
P2093
P2860
P1433
P1476
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma
@en
P2093
Chiara Bardella
Daniel Krell
Malcolm Galloway
Mawuelikem Assoku
Paul Mulholland
P2860
P304
P356
10.1371/JOURNAL.PONE.0019868
P407
P577
2011-05-23T00:00:00Z