Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation - Wikidata - wikimedia - TriplyDB

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

http://www.wikidata.org/entity/Q34034515

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The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1 Regulation of nuclear factor-κB in autoimmunity Immune-pineal axis: nuclear factor κB (NF-kB) mediates the shift in the melatonin source from pinealocytes to immune competent cells NF-κB in inflammation and renal diseases Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures Structure of the Nuclear Factor B-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host DMA, a bisbenzimidazole, offers radioprotection by promoting NFκB transactivation through NIK/IKK in human glioma cells NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.The noncanonical NF-κB pathway.IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.Anion-exchange chromatography of phosphopeptides: weak anion exchange versus strong anion exchange and anion-exchange chromatography versus electrostatic repulsion-hydrophilic interaction chromatography Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis NF-κB and cancer: a paradigm of Yin-Yang.Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease Mono-(2-Ethylhexyl) Phthalate Promotes Pro-Labor Gene Expression in the Human Placenta.Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.K63-linked ubiquitination in kinase activation and cancer.NLRP12 provides a critical checkpoint for osteoclast differentiation The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells.Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival Context-specific BAFF-R signaling by the NF-κB and PI3K pathways Noncanonical NF-κB signaling is limited by classical NF-κB activity.A single NFκB system for both canonical and non-canonical signaling.Non-canonical NF-κB signaling pathway.Negative regulation of NF-κB and its involvement in rheumatoid arthritis.Return to homeostasis: downregulation of NF-κB responses.Non-canonical NF-κB signaling activation and regulation: principles and perspectives.Subversion of innate immune responses by bacterial hindrance of NF-κB pathway.Viral interference with innate immunity by preventing NF-κB activity.Regulation of NF-κB by TNF family cytokines.Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression.A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes.High Endothelial Venules and Other Blood Vessels: Critical Regulators of Lymphoid Organ Development and Function The non-canonical NF-κB pathway in immunity and inflammation.NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-κB pathway NF-κB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells.

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P2860

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

http://www.wikidata.org/entity/Q34034515

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

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2010年學術文章

@yue

name

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@ast

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@en

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@nl

type

label

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@ast

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@en

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@nl

prefLabel

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@ast

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@en

Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@nl

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Science Signaling

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Negative feedback in noncanoni ...... alpha-mediated phosphorylation

@en

P2093

A Jimmy Ytterberg

http://www.w3.org/2001/XMLSchema#string

Bahram Razani

http://www.w3.org/2001/XMLSchema#string

Brian Zarnegar

http://www.w3.org/2001/XMLSchema#string

Carl F Ware

http://www.w3.org/2001/XMLSchema#string

Joseph A Loo

http://www.w3.org/2001/XMLSchema#string

Paul W Dempsey

http://www.w3.org/2001/XMLSchema#string

Travis Shiba

http://www.w3.org/2001/XMLSchema#string

P2860

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

Ubiquitin-dependent protein degradation

Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

NF-kappaB and the immune response

Ubiquitin-independent degradation of proteins by the proteasome

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

NF-kappa B: ten years after

Sample purification and preparation technique based on nano-scale reversed-phase columns for the sensitive analysis of complex peptide mixtures by matrix-assisted laser desorption/ionization mass spectrometry.

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10.1126/SCISIGNAL.2000778

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123

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3

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44629820

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20501937

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phosphorylation

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2913610

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