about
Evolutionary Ecology of Prokaryotic Immune MechanismsNovel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationThe expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactionsStructures of a CRISPR-Cas9 R-loop complex primed for DNA cleavageThe crystal structure of Cpf1 in complex with CRISPR RNAA CRISPR toolbox to study virus-host interactionsThe spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer.Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.The CCTL (Cpf1-assisted Cutting and Taq DNA ligase-assisted Ligation) method for efficient editing of large DNA constructs in vitroStructural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity.Multiplex gene regulation by CRISPR-ddCpf1Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.MIMIVIRE is a defence system in mimivirus that confers resistance to virophage.Development of CRISPR/Cas9 for Efficient Genome Editing in Toxoplasma gondii.The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.Induced Pluripotent Stem Cells Meet Genome EditingC2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Applications of CRISPR technologies in research and beyond.Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergenceGenome-scale CRISPR-Cas9 knockout and transcriptional activation screeningCrystal Structure of Cpf1 in Complex with Guide RNA and Target DNACasposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systemsCoupling immunity and programmed cell suicide in prokaryotes: Life-or-death choices.Diversity and evolution of class 2 CRISPR-Cas systems.Not all predicted CRISPR-Cas systems are equal: isolated cas genes and classes of CRISPR like elements.Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery.A highly specific phage defense system is a conserved feature of the Vibrio cholerae mobilomeA Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms.Harnessing the Prokaryotic Adaptive Immune System as a Eukaryotic Antiviral Defense.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchCRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis.Introduction to Gene Editing and Manipulation Using CRISPR/Cas9 Technology.Easy regulation of metabolic flux in Escherichia coli using an endogenous type I-E CRISPR-Cas system.CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modeling.Sensing danger.Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system.The quantum mitochondrion and optimal health.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
name
CRISPR-Cas immunity in prokaryotes.
@ast
CRISPR-Cas immunity in prokaryotes.
@en
CRISPR-Cas immunity in prokaryotes.
@nl
type
label
CRISPR-Cas immunity in prokaryotes.
@ast
CRISPR-Cas immunity in prokaryotes.
@en
CRISPR-Cas immunity in prokaryotes.
@nl
prefLabel
CRISPR-Cas immunity in prokaryotes.
@ast
CRISPR-Cas immunity in prokaryotes.
@en
CRISPR-Cas immunity in prokaryotes.
@nl
P2860
P356
P1433
P1476
CRISPR-Cas immunity in prokaryotes.
@en
P2093
Luciano A Marraffini
P2860
P2888
P356
10.1038/NATURE15386
P407
P577
2015-10-01T00:00:00Z