Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.
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Different Subsets of T Cells, Memory, Effector Functions, and CAR-T ImmunotherapyImmunotherapy in human colorectal cancer: Challenges and prospectiveTechnical Considerations for the Generation of Adoptively Transferred T Cells in Cancer ImmunotherapyImmunometabolism of regulatory T cellsChimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor ImmunityMitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma.Intent-to-treat leukemia remission by CD19 CAR T cells of defined formulation and dose in children and young adultsIncorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells.Fully human CD19-specific chimeric antigen receptors for T-cell therapy.The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesTh17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion.Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy.Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo.Driving gene-engineered T cell immunotherapy of cancer.Recent advances in T-cell immunotherapy for haematological malignancies.Chimeric antigen receptor-modified T cells for the treatment of solid tumors: Defining the challenges and next steps.Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers.The growing world of CAR T cell trials: a systematic review.Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse.CD19-Targeted CAR T cells as novel cancer immunotherapy for relapsed or refractory B-cell acute lymphoblastic leukemia.Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials.The promise of chimeric antigen receptor T cells (CARTs) in leukaemia.Adoptive cellular immunotherapy for virus-associated cancers: a new paradigm in personalized medicine.CAR T-cell therapy of solid tumors.The Principles of Engineering Immune Cells to Treat Cancer.Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines.Constitutive Glycolytic Metabolism Supports CD8(+) T Cell Effector Memory Differentiation during Viral Infection.Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment.Fine tuning of immunometabolism for the treatment of rheumatic diseases.Mitochondria are the powerhouses of immunity.Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the FuelSynthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.Dysfunctional T cell metabolism in the tumor microenvironment.Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries.Metabolic Instruction of Immunity.Engineering CAR-T cells.Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy.Therapeutic T cell engineering.Mesothelin-targeting chimeric antigen receptor-modified T cells by piggyBac transposon system suppress the growth of bile duct carcinoma.Driving better and safer HER2-specific CARs for cancer therapy.
P2860
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P2860
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.
description
2016 nî lūn-bûn
@nan
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@ast
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@en
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@nl
type
label
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@ast
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@en
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@nl
prefLabel
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@ast
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@en
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@nl
P2093
P1433
P1476
Distinct Signaling of Corecept ...... ry Development in CAR T Cells.
@en
P2093
Avery D Posey
Brian Keith
Carl H June
Ian A Blair
John Scholler
Joseph A Fraietta
Michael C Milone
Nathaniel W Snyder
Omkar U Kawalekar
P304
P356
10.1016/J.IMMUNI.2016.01.021
P407
P577
2016-02-01T00:00:00Z