FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction
about
Protein kinases and phosphatases in the control of cell fateFeature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiologyRheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signalingSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsMechanical Signaling in the Pathophysiology of Critical Illness MyopathyMitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer TherapyRegulation of pol III transcription by nutrient and stress signaling pathwaysMechanisms of mitochondria and autophagy crosstalkmTOR and differential activation of mitochondria orchestrate neutrophil chemotaxisStructural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic MicellesNutrient regulates Tor1 nuclear localization and association with rDNA promoter.The yeast deubiquitinating enzyme Ubp16 is anchored to the outer mitochondrial membrane.mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and agingHyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytesHepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinaseIntracellular water homeostasis and the mammalian cellular osmotic stress responseSpecific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolismWhere is mTOR and what is it doing there?The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunitymTOR regulation of autophagyTOR signaling.Cell growth control: little eukaryotes make big contributions.Target of rapamycin and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii.Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats.Direct control of mitochondrial function by mTOR.ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia.Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.Pathogenic mechanisms in systemic lupus erythematosus.Oxidative stress in the pathology and treatment of systemic lupus erythematosusHRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.T-cell and B-cell signaling biomarkers and treatment targets in lupus.mTOR signaling in lymphangioleiomyomatosisWith TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in agingAttenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetesTarget of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.A systematic characterization of mitochondrial proteome from human T leukemia cellsBcl2's flexible loop domain regulates p53 binding and survivalActivation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
P2860
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P2860
FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@ast
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@en
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@nl
type
label
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@ast
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@en
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@nl
prefLabel
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@ast
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@en
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@nl
P2860
P356
P1476
FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction
@en
P2093
Benjamin R Myers
Stuart L Schreiber
P2860
P304
P356
10.1073/PNAS.261702698
P407
P577
2002-04-01T00:00:00Z