FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction - Wikidata - wikimedia - TriplyDB

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

http://www.wikidata.org/entity/Q34047681

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Protein kinases and phosphatases in the control of cell fate Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy Regulation of pol III transcription by nutrient and stress signaling pathways Mechanisms of mitochondria and autophagy crosstalk mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis Structural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic Micelles Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.The yeast deubiquitinating enzyme Ubp16 is anchored to the outer mitochondrial membrane.mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase Intracellular water homeostasis and the mammalian cellular osmotic stress response Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism Where is mTOR and what is it doing there?The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity mTOR regulation of autophagy TOR signaling.Cell growth control: little eukaryotes make big contributions.Target of rapamycin and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii.Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats.Direct control of mitochondrial function by mTOR.ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia.Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.Pathogenic mechanisms in systemic lupus erythematosus.Oxidative stress in the pathology and treatment of systemic lupus erythematosus HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.T-cell and B-cell signaling biomarkers and treatment targets in lupus.mTOR signaling in lymphangioleiomyomatosis With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.A systematic characterization of mitochondrial proteome from human T leukemia cells Bcl2's flexible loop domain regulates p53 binding and survival Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

P2860

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P2860

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

http://www.wikidata.org/entity/Q34047681

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

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FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

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FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

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type

label

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

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FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

@en

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

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prefLabel

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

@ast

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

@en

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

@nl

P1433

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Proceedings of the National Academy of Sciences of the United States of America

P1476

FKBP12-rapamycin-associated pr ...... via mitochondrial dysfunction

@en

P2093

Benjamin R Myers

http://www.w3.org/2001/XMLSchema#string

Stuart L Schreiber

http://www.w3.org/2001/XMLSchema#string

P2860

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

TOR, a central controller of cell growth.

BCL-2 family members and the mitochondria in apoptosis

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

Structural and functional analysis of pp70S6k.

4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle.

Mammalian TOR: a homeostatic ATP sensor.

Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).

Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells.

Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase.

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4319-4324

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scholarly article

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10.1073/PNAS.261702698

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7

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99

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2002-04-01T00:00:00Z

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11435513

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11930000

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123646

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