The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining.
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MYC oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regionsMolecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patientEpstein-Barr virus and Burkitt lymphomaTwenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clusteringFrequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain diseaseDifferent regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.Cloning of the gene encoding the delta subunit of the human T-cell receptor reveals its physical organization within the alpha-subunit locus and its involvement in chromosome translocations in T-cell malignancy.Lymphoma stem cells: enough evidence to support their existence?Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasiaGenetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase.Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocationA deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors.Epstein-Barr virus-transformed pro-B cells are prone to illegitimate recombination between the switch region of the mu chain gene and other chromosomesMolecular resemblance of an AIDS-associated lymphoma and endemic Burkitt lymphomas: implications for their pathogenesis.AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.The t(8;14) chromosome translocation of the Burkitt lymphoma cell line Daudi occurred during immunoglobulin gene rearrangement and involved the heavy chain diversity region.Mechanisms of chromosomal translocations in B cell lymphomas.Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas.An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiaeConservation and continuity of periodic bent DNA in genomic rearrangements between the c-myc and immunoglobulin heavy chain mu lociN segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation.Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential.Comparative mapping of the constitutional and tumor-associated 11;22 translocations.The association of c-myc rearrangements with specific types of human non-Hodgkin's lymphomas.Molecular genetic analysis of lymphoid tumors arising after organ transplantation.Epstein-Barr virus induction of recombinase-activating genes RAG1 and RAG2V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development.The t(8;14) breakpoint of the EW 36 undifferentiated lymphoma cell line lies 5' of MYC in a region prone to involvement in endemic Burkitt's lymphomas.Context-specific roles for paracrine IL-6 in lymphomagenesis.Somatic mutation and transcriptional deregulation of myc in endemic Burkitt's lymphoma disease: heptamer-nonamer recognition mistakes?Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation.6;7 chromosomal translocation in spontaneously arising rat immunocytomas: evidence for c-myc breakpoint clustering and correlation between isotypic expression and the c-myc target.A complex translocation at the murine kappa light-chain locus.MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs.The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinaseMolecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigenThe role of the bcl-2 gene in lymphoma.An overview of tumor biology.Directional genomic hybridization for chromosomal inversion discovery and detection.V(D)J Recombination: Mechanism, Errors, and Fidelity.
P2860
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P2860
The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining.
description
1986 nî lūn-bûn
@nan
1986 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@ast
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@en
type
label
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@ast
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@en
prefLabel
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@ast
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@en
P2093
P356
P1433
P1476
The t(8; 14) chromosomal trans ...... rom mistakes in V-D-J joining.
@en
P2093
P2888
P304
P356
10.1038/324158A0
P407
P577
1986-11-01T00:00:00Z
P6179
1045801329