Topological structure of the space of phenotypes: the case of RNA neutral networks
about
Distribution of genotype network sizes in sequence-to-structure genotype-phenotype maps.Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms.Human genome variation and the concept of genotype networks.The involvement of thaumatin-like proteins in plant food cross-reactivity: a multicenter study using a specific protein microarrayGraph based study of allergen cross-reactivity of plant lipid transfer proteins (LTPs) using microarray in a multicenter study.Evolution on neutral networks accelerates the ticking rate of the molecular clockGenetic Correlations Greatly Increase Mutational Robustness and Can Both Reduce and Enhance Evolvability.A quantitative quasispecies theory-based model of virus escape mutation under immune selectionQuantitative modeling of virus evolutionary dynamics and adaptation in serial passages using empirically inferred fitness landscapesA tractable genotype-phenotype map modelling the self-assembly of protein quaternary structure.Structural properties of genotype-phenotype maps.The organization of biological sequences into constrained and unconstrained parts determines fundamental properties of genotype-phenotype maps.toyLIFE: a computational framework to study the multi-level organisation of the genotype-phenotype map.Adaptive multiscapes: an up-to-date metaphor to visualize molecular adaptation.The structure of the genotype-phenotype map strongly constrains the evolution of non-coding RNA.RNA Virus Evolution via a Quasispecies-Based Model Reveals a Drug Target with a High Barrier to Resistance.Proteins with Highly Evolvable Domain Architectures Are Nonessential but Highly Retained.Origin of life in a digital microcosm.Phenotypes can be robust and evolvable if mutations have non-local effects on sequence constraints.Adding levels of complexity enhances robustness and evolvability in a multilevel genotype-phenotype map.Surviving evolutionary escape on complex genotype-phenotype networks.The architecture of an empirical genotype-phenotype map.RNA-mediated gene regulation is less evolvable than transcriptional regulation.On the networked architecture of genotype spaces and its critical effects on molecular evolution
P2860
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P2860
Topological structure of the space of phenotypes: the case of RNA neutral networks
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Topological structure of the space of phenotypes: the case of RNA neutral networks
@ast
Topological structure of the space of phenotypes: the case of RNA neutral networks
@en
Topological structure of the space of phenotypes: the case of RNA neutral networks
@nl
type
label
Topological structure of the space of phenotypes: the case of RNA neutral networks
@ast
Topological structure of the space of phenotypes: the case of RNA neutral networks
@en
Topological structure of the space of phenotypes: the case of RNA neutral networks
@nl
prefLabel
Topological structure of the space of phenotypes: the case of RNA neutral networks
@ast
Topological structure of the space of phenotypes: the case of RNA neutral networks
@en
Topological structure of the space of phenotypes: the case of RNA neutral networks
@nl
P2860
P50
P1433
P1476
Topological structure of the space of phenotypes: the case of RNA neutral networks
@en
P2093
Michael Stich
P2860
P304
P356
10.1371/JOURNAL.PONE.0026324
P407
P577
2011-10-18T00:00:00Z