Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics.
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Paclitaxel-dependent cell lines reveal a novel drug activity.Modulation of Protein-Protein Interactions for the Development of Novel TherapeuticsBrain-Specific Cytoskeletal Damage Markers in Cerebrospinal Fluid: Is There a Common Pattern between Amyotrophic Lateral Sclerosis and Primary Progressive Multiple Sclerosis?Vinca alkaloidsMultiple tubulins: evolutionary aspects and biological implicationsSpatiotemporal quantification of subcellular ATP levels in a single HeLa cell during changes in morphology.Chemotaxis of cell populations through confined spaces at single-cell resolutionAn inhibitor of FtsZ with potent and selective anti-staphylococcal activityPlasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partitionHuman Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNATargeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapyCyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.Megakaryocyte lineage-specific class VI β-tubulin suppresses microtubule dynamics, fragments microtubules, and blocks cell division.Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation.Cytoskeletal changes in actin and microtubules underlie the developing surface mechanical properties of sensory and supporting cells in the mouse cochlea.MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.Outcome Measures in Clinical Trials for Multiple Sclerosis.Effect of water-soluble fraction of cigarette smoke on human aortic endothelial cells--a proteomic approach.Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cellsRabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implicationsMechanisms of Taxol resistance related to microtubules.Acetylated microtubules are required for fusion of autophagosomes with lysosomesMicrotubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolideNovel response to microtubule perturbation in meiosis.One-way ticket to the cell pole: plasmid transport by the prokaryotic tubulin homolog TubZ.Evolution of the total syntheses of ustiloxin natural products and their analoguesMobility of taxol in microtubule bundles.Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions.Bacterial plasmid partition machinery: a minimalist approach to survival.Expression of hNP22 is altered in the frontal cortex and hippocampus of the alcoholic human brain.Highly dynamic microtubules improve the effectiveness of early stages of human influenza A/NWS/33 virus infection in LLC-MK2 cells.Clinical trials and progress with paclitaxel in ovarian cancerMicrotubule-stabilizing agents based on designed laulimalide analogues.Unprecedented inhibition of tubulin polymerization directed by gold nanoparticles inducing cell cycle arrest and apoptosis.Design, Synthesis and Cytotoxicity Evaluationof New 1,2-diaryl-4, 5, 6, 7-Tetrahydro-1H-benzo[d] Imidazolesas Tubulin Inhibitors.Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.Promising therapeutic targets for antileishmanial drugs.Enhancement of microtubule-associated protein-1 Alpha gene expression in osteoblasts by low level laser irradiation.
P2860
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P2860
Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural basis for the inter ...... t affect microtubule dynamics.
@ast
Structural basis for the inter ...... t affect microtubule dynamics.
@en
Structural basis for the inter ...... t affect microtubule dynamics.
@nl
type
label
Structural basis for the inter ...... t affect microtubule dynamics.
@ast
Structural basis for the inter ...... t affect microtubule dynamics.
@en
Structural basis for the inter ...... t affect microtubule dynamics.
@nl
prefLabel
Structural basis for the inter ...... t affect microtubule dynamics.
@ast
Structural basis for the inter ...... t affect microtubule dynamics.
@en
Structural basis for the inter ...... t affect microtubule dynamics.
@nl
P1476
Structural basis for the inter ...... t affect microtubule dynamics.
@en
P2093
Downing KH
P304
P356
10.1146/ANNUREV.CELLBIO.16.1.89
P577
2000-01-01T00:00:00Z