The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone. - Wikidata - wikimedia - TriplyDB

The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.

The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.

http://www.wikidata.org/entity/Q34061985

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Mutational profiling of kinases in glioblastoma.Current status of biomarker research in neurology Advances in the treatment of newly diagnosed glioblastoma Clinical and biological implications of ancestral and non-ancestral IDH1 and IDH2 mutations in myeloid neoplasms 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.Contribution of the Microenvironmental Niche to Glioblastoma Heterogeneity.IDH-Mutation Is a Weak Predictor of Long-Term Survival in Glioblastoma Patients.MGMT testing allows for personalised therapy in the temozolomide era.Radiological features combined with IDH1 status for predicting the survival outcome of glioblastoma patients.Prognostic Stratification of GBMs Using Combinatorial Assessment of IDH1 Mutation, MGMT Promoter Methylation, and TERT Mutation Status: Experience from a Tertiary Care Center in India.Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor.Stem cell niche irradiation in glioblastoma: providing a ray of hope?Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours Delivery of local therapeutics to the brain: working toward advancing treatment for malignant gliomas.Recent developments in predictive biomarkers of pediatric glioma In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma Neural stem cells, the subventricular zone and radiotherapy: implications for treating glioblastoma.Isocitrate Dehydrogenase (IDH)1/2 Mutations as Prognostic Markers in Patients With Glioblastomas The impact of MGMT methylation and IDH-1 mutation on long-term outcome for glioblastoma treated with chemoradiotherapy.Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.High CD133 Expression Is Associated with Worse Prognosis in Patients with Glioblastoma.Prognostic role of IDH mutations in gliomas: a meta-analysis of 55 observational studies.Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas.Genomic and Molecular Characterization of Brain Tumors in Asian and Non-Asian Patients of Los Angeles: A Single Institution Analysis.PDGF Family Expression in Glioblastoma Multiforme: Data Compilation from Ivy Glioblastoma Atlas Project Database.Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins.Wild-type and mutated IDH1/2 enzymes and therapy responses.Temporal stability of MGMT promoter methylation in glioblastoma patients undergoing STUPP protocol.Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.Glioblastomas with IDH1/2 mutations have a short clinical history and have a favorable clinical outcome.Assessment of molecular markers demonstrates concordance between samples acquired via stereotactic biopsy and open craniotomy in both anaplastic astrocytomas and glioblastomas.Assessment of the Association between Isocitrate Dehydrogenase 1 Mutation and Mortality Risk of Glioblastoma Patients.DNM3, p65 and p53 from exosomes represent potential clinical diagnosis markers for glioblastoma multiforme.Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies.Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer.Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs.Survival prediction based on qualitative MRI diffusion signature in patients with recurrent high grade glioma treated with bevacizumab.dbLGL: an online leukemia gene and literature database for the retrospective comparison of adult and childhood leukemia genetics with literature evidence.A Visually Interpretable, Dictionary-Based Approach to Imaging-Genomic Modeling, With Low-Grade Glioma as a Case Study Nanotechnology for treatment of glioblastoma multiforme

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P2860

The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.

http://www.wikidata.org/entity/Q34061985

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

@zh-tw

2014年论文

@wuu

name

The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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type

label

The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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prefLabel

The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... han either IDH1 or MGMT alone.

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The combination of IDH1 mutati ...... than either IDH1 or MGMT alone

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Alberto Bardelli

http://www.w3.org/2001/XMLSchema#string

Angela A van Tilborg

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Carlo Zanon

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Cornelis J F van Noorden

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Dirk Troost

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Fonnet E Bleeker

http://www.w3.org/2001/XMLSchema#string

Judith W M Jeuken

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Remco J Molenaar

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Sandra H E Boots-Sprenger

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Sieger Leenstra

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P2860

Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Recent advances in the molecular understanding of glioblastoma

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

The Catalogue of Somatic Mutations in Cancer (COSMIC)

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

Multiplex ligation-dependent probe amplification: a diagnostic tool for simultaneous identification of different genetic markers in glial tumors

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1263-1273

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scholarly article

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10.1093/NEUONC/NOU005

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9

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16

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Pieter Wesseling

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2014-02-06T00:00:00Z

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260131052

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24510240

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4136888

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