A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway. - Wikidata - wikimedia - TriplyDB

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

http://www.wikidata.org/entity/Q34064121

about

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library Viral transport of DNA damage that mimics a stalled replication fork.Checkpoint independence of most DNA replication origins in fission yeast RecQ helicases: guardian angels of the DNA replication fork.Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage.Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival.Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.RecQ helicases: at the heart of genetic stability.Identification of MCM4 as a target of the DNA replication block checkpoint system.Human TopBP1 ensures genome integrity during normal S phase A postsynaptic role for Rhp55/57 that is responsible for cell death in Deltarqh1 mutants following replication arrest in Schizosaccharomyces pombe Stimulation of human DNA polymerase epsilon by MDM2 A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1 RecQ helicases: suppressors of tumorigenesis and premature aging.Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers.Structure and function of RecQ DNA helicases.Checkpoint-dependent regulation of origin firing and replication fork movement in response to DNA damage in fission yeast.A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1.The Mcm complex: unwinding the mechanism of a replicative helicase.The unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms.Cell-cycle-specific activators of the Mec1/ATR checkpoint kinase.Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast.The N-terminal 45-kDa domain of Dna2 endonuclease/helicase targets the enzyme to secondary structure DNA The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.A role for the phosphorylation of hRad9 in checkpoint signaling.Meiotic S-phase damage activates recombination without checkpoint arrest.High dosage Rhp51 suppression of the MMS sensitivity of DNA structure checkpoint mutants reveals a relationship between Crb2 and Rhp51.Schizosaccharomyces pombe Ddb1 is functionally linked to the replication checkpoint pathway.Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress.

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A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

http://www.wikidata.org/entity/Q34064121

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

name

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@ast

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@en

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

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type

label

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@ast

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@en

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@nl

prefLabel

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@ast

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@en

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.

@en

P2093

Edgar Hartsuiker

http://www.w3.org/2001/XMLSchema#string

Greg A Freyer

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Joel A Huberman

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Maria A Marchetti

http://www.w3.org/2001/XMLSchema#string

Mohamed Maftahi

http://www.w3.org/2001/XMLSchema#string

Sanjay Kumar

http://www.w3.org/2001/XMLSchema#string

William C Burhans

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P2860

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

Evolutionary conservation of excision repair in Schizosaccharomyces pombe: evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 gene

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast

DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.

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7472-7477

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scholarly article

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10.1073/PNAS.112702399

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11

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99

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2002-05-01T00:00:00Z

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11340815

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12032307

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124255

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