Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.
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Transport mechanism of a glutamate transporter homologue GltPhVisualizing functional motions of membrane transporters with molecular dynamics simulationsMechanisms of glutamate transportExcitatory amino acid transporters: roles in glutamatergic neurotransmissionMolecular dynamics simulations of the mammalian glutamate transporter EAAT3Binding thermodynamics of a glutamate transporter homologCoupled ion binding and structural transitions along the transport cycle of glutamate transportersCrystal structure of a substrate-free aspartate transporterMolecular dynamics simulations elucidate the mechanism of proton transport in the glutamate transporter EAAT3Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1.The use of Xenopus oocytes in drug screening.Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophreniaAn entropic mechanism of generating selective ion binding in macromolecules.Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrateFree energy simulations of ligand binding to the aspartate transporter Glt(Ph).Current and selectivity in a model sodium channel under physiological conditions: Dynamic Monte Carlo simulations.Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding SiteA conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transportersStructural intermediates in a model of the substrate translocation path of the bacterial glutamate transporter homologue GltPh.Conserved asparagine residue located in binding pocket controls cation selectivity and substrate interactions in neuronal glutamate transporter.Molecular Determinants of Substrate Specificity in Sodium-coupled Glutamate Transporters.The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2.Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP.Computational Studies of Glutamate TransportersProtonation state of a conserved acidic amino acid involved in Na(+) binding to the glutamate transporter EAAC1Cysteine scanning mutagenesis of transmembrane helix 3 of a brain glutamate transporter reveals two conformationally sensitive positionsVoltage-dependent processes in the electroneutral amino acid exchanger ASCT2Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes.SLC1 glutamate transportersNeurotransmitter transporters: structure meets function.Glutamate Transporters/Na(+), K(+)-ATPase Involving in the Neuroprotective Effect as a Potential Regulatory Target of Glutamate Uptake.Ion channels and ion selectivity.Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations.Coupling between neurotransmitter translocation and protonation state of a titratable residue during Na ⁺-coupled transport.Low Affinity and Slow Na+ Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter GltPh.A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters.Neutralizing aspartate 83 modifies substrate translocation of excitatory amino acid transporter 3 (EAAT3) glutamate transporters.Structure and allosteric inhibition of excitatory amino acid transporter 1.Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.Insights on Na(+) binding and conformational dynamics in multidrug and toxic compound extrusion transporter NorM.
P2860
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P2860
Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@ast
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@en
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@nl
type
label
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@ast
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@en
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@nl
prefLabel
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@ast
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@en
Evidence for a third sodium-bi ...... ion/substrate coupling model.
@nl
P2093
P2860
P50
P356
P1476
Evidence for a third sodium-bi ...... n ion/substrate coupling model
@en
P2093
Ana Diez-Sampedro
H Peter Larsson
Hans P Koch
Isabelle Baconguis
Nicholas P Vyleta
Xiaoyu Wang
P2860
P304
13912-13917
P356
10.1073/PNAS.1006289107
P407
P577
2010-07-15T00:00:00Z