Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model. - Wikidata - wikimedia - TriplyDB

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.

http://www.wikidata.org/entity/Q34068453

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Transport mechanism of a glutamate transporter homologue GltPh Visualizing functional motions of membrane transporters with molecular dynamics simulations Mechanisms of glutamate transport Excitatory amino acid transporters: roles in glutamatergic neurotransmission Molecular dynamics simulations of the mammalian glutamate transporter EAAT3 Binding thermodynamics of a glutamate transporter homolog Coupled ion binding and structural transitions along the transport cycle of glutamate transporters Crystal structure of a substrate-free aspartate transporter Molecular dynamics simulations elucidate the mechanism of proton transport in the glutamate transporter EAAT3 Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1.The use of Xenopus oocytes in drug screening.Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia An entropic mechanism of generating selective ion binding in macromolecules.Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrate Free energy simulations of ligand binding to the aspartate transporter Glt(Ph).Current and selectivity in a model sodium channel under physiological conditions: Dynamic Monte Carlo simulations.Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site A conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transporters Structural intermediates in a model of the substrate translocation path of the bacterial glutamate transporter homologue GltPh.Conserved asparagine residue located in binding pocket controls cation selectivity and substrate interactions in neuronal glutamate transporter.Molecular Determinants of Substrate Specificity in Sodium-coupled Glutamate Transporters.The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2.Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP.Computational Studies of Glutamate Transporters Protonation state of a conserved acidic amino acid involved in Na(+) binding to the glutamate transporter EAAC1 Cysteine scanning mutagenesis of transmembrane helix 3 of a brain glutamate transporter reveals two conformationally sensitive positions Voltage-dependent processes in the electroneutral amino acid exchanger ASCT2 Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes.SLC1 glutamate transporters Neurotransmitter transporters: structure meets function.Glutamate Transporters/Na(+), K(+)-ATPase Involving in the Neuroprotective Effect as a Potential Regulatory Target of Glutamate Uptake.Ion channels and ion selectivity.Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations.Coupling between neurotransmitter translocation and protonation state of a titratable residue during Na ⁺-coupled transport.Low Affinity and Slow Na+ Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter GltPh.A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters.Neutralizing aspartate 83 modifies substrate translocation of excitatory amino acid transporter 3 (EAAT3) glutamate transporters.Structure and allosteric inhibition of excitatory amino acid transporter 1.Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.Insights on Na(+) binding and conformational dynamics in multidrug and toxic compound extrusion transporter NorM.

P2860

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P2860

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.

http://www.wikidata.org/entity/Q34068453

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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Evidence for a third sodium-bi ...... ion/substrate coupling model.

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PNAS.1006289107

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Proceedings of the National Academy of Sciences of the United States of America

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Evidence for a third sodium-bi ...... n ion/substrate coupling model

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P2093

Ana Diez-Sampedro

http://www.w3.org/2001/XMLSchema#string

H Peter Larsson

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Hans P Koch

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Isabelle Baconguis

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Nicholas P Vyleta

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Xiaoyu Wang

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P2860

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

Glutamate uptake

Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters

Flux coupling in a neuronal glutamate transporter

Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

Structure of a glutamate transporter homologue from Pyrococcus horikoshii.

Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter.

Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1

Trimeric subunit stoichiometry of the glutamate transporters from Bacillus caldotenax and Bacillus stearothermophilus.

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31

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107

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Sergei Y Noskov

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2010-07-15T00:00:00Z

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45200000

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20634426

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2922246

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